Fatigue, sleep, and autoimmune and related disorders

MR Zielinski, DM Systrom, NR Rose - Frontiers in immunology, 2019 - frontiersin.org
Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Role of dopamine neurons in reward and aversion: a synaptic plasticity perspective

M Pignatelli, A Bonci - Neuron, 2015 - cell.com
The brain is wired to predict future outcomes. Experience-dependent plasticity at excitatory
synapses within dopamine neurons of the ventral tegmental area, a key region for a broad …

The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota

P Bermudez-Martin, JAJ Becker, N Caramello… - Microbiome, 2021 - Springer
Background Autism spectrum disorders (ASD) are associated with dysregulation of the
microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum …

Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis

A Aransay, C Rodríguez-López… - Frontiers in …, 2015 - frontiersin.org
Pathways arising from the ventral tegmental area (VTA) release dopamine and other
neurotransmitters during the expectation and achievement of reward, and are regarded as …

One water-soluble polysaccharide from Ginkgo biloba leaves with antidepressant activities via modulation of the gut microbiome

P Chen, M Hei, L Kong, Y Liu, Y Yang, H Mu… - Food & function, 2019 - pubs.rsc.org
Depression, a mental illness characterized by persistent feeling of sadness and loss of
interest, has been a serious health problem worldwide. Manipulation of the microbiota by …

Neurocircuitry of aggression and aggression seeking behavior: nose poking into brain circuitry controlling aggression

H Aleyasin, ME Flanigan, SJ Russo - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Cell-specific strategies to study microcircuitries that modulate aggression.•Brain
systems that control the valence of aggressive behavior.•Aggression-seeking models that …

Functional neuroanatomical review of the ventral tegmental area

AC Trutti, MJ Mulder, B Hommel, BU Forstmann - Neuroimage, 2019 - Elsevier
The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to
play a key role in dopamine-related functions such as reward-related behaviour, motivation …

Functional connectivity disturbances of the ascending reticular activating system in temporal lobe epilepsy

DJ Englot, PF D'Haese, PE Konrad… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective Seizures in temporal lobe epilepsy (TLE) disturb brain networks and lead to
connectivity disturbances. We previously hypothesised that recurrent seizures in TLE may …

The lateral hypothalamus: an uncharted territory for processing peripheral neurogenic inflammation

M Fakhoury, I Salman, W Najjar, G Merhej… - Frontiers in …, 2020 - frontiersin.org
The roles of the hypothalamus and particularly the lateral hypothalamus (LH) in the
regulation of inflammation and pain have been widely studied. The LH consists of a …

History of early life adversity is associated with increased food addiction and sex‐specific alterations in reward network connectivity in obesity

V Osadchiy, EA Mayer, R Bhatt, JS Labus… - Obesity science & …, 2019 - Wiley Online Library
Background Neuroimaging studies have identified obesity‐related differences in the brain's
resting state activity. An imbalance between homeostatic and reward aspects of ingestive …