Transmission of pain signals evoked by tissue damage leads to sensitization of the
peripheral and central pain pathways. Pre-emptive analgesia is a treatment that is initiated …

The classic definition of preemptive analgesia requires 2 groups of patients to receive
identical treatment before or after incision or surgery. The only difference between the 2 …

在急性疼痛治疗中, 尤其是在术后患者自控镇痛(patient controlled analgesia) 时,
超前镇痛或预先镇痈(pre-emptive analgesia) 是人们常提及的治疗方法口'2] …

Despite efforts to recognize the undertreatment of perioperative pain and promulgate
guidelines to improve this situation [1], perioperative pain remains prevalent and is one of …

Background The aim of this study was to evaluate the postoperative morphine-sparing
effects and reduction in pain and secondary mechanical hyperalgesia after preincisional or …

The management of acute postoperative pain has been dominated by an outdated
conceptualization of pain. Pain is viewed as the end-product of a passive transmission …

Clinical studies that have used the third molar extraction model for acute post-operative
dental pain have demonstrated the usefulness of nonsteroidal anti-inflammatory drugs …

Hypersensitivity after tissue injury is an expression of neuronal plasticity in the central
nervous system. This has been explored most extensively using in vitro preparations and …

The authors examined whether ketoprofen administered 60min before surgical extraction of
the lower wisdom teeth provides effective postsurgical analgesia and reduces rescue …

New animal models of peripheral nerve injury have facilitated our understanding of
neuropathic pain mechanisms. Nerve injury increases expression and redistribution of …