Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer

B Goyal, SRM Yadav, N Awasthee, S Gupta… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a widely
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …

[HTML][HTML] Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers

N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

[HTML][HTML] Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

[HTML][HTML] Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis

ST Xue, B Zheng, SQ Cao, JC Ding, GS Hu, W Liu… - Molecular cancer, 2022 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is a common invasive
malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding …

[HTML][HTML] Biomarkers of gastric cancer: Current topics and future perspective

T Matsuoka, M Yashiro - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the most prevalent malignant types in the world and an
aggressive disease with a poor 5-year survival. This cancer is biologically and genetically …

microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance

M Fattahi, S Shahrabi, F Saadatpour, D Rezaee… - International journal of …, 2023 - Elsevier
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …

[HTML][HTML] Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”

K Grillone, C Riillo, F Scionti, R Rocca… - Journal of Experimental …, 2020 - Springer
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

S Mishra, SS Verma, V Rai, N Awasthee… - Cellular and Molecular …, 2019 - Springer
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

[HTML][HTML] Crosstalk between long non-coding RNAs, micro-RNAs and mRNAs: deciphering molecular mechanisms of master regulators in cancer

E López-Urrutia, LP Bustamante Montes… - Frontiers in …, 2019 - frontiersin.org
Cancer is a complex disease, and its study requires deep understanding of several
biological processes and their regulation. It is an accepted fact that non-coding RNAs are …

[HTML][HTML] LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer

G Zhang, S Li, J Lu, Y Ge, Q Wang, G Ma, Q Zhao… - Molecular cancer, 2018 - Springer
Background Emerging evidence has shown that dysregulation function of long non-coding
RNAs (lncRNAs) implicated in gastric cancer (GC). However, the role of the differentially …