Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability

GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions

M Hashemi, HZ Arani, S Orouei, E Rostamnejad… - Pharmacological …, 2022 - Elsevier
Urological cancers are considered as life-threatening diseases around the world. Bladder
cancer is one of the most malignant urological tumors with high mortality and morbidity …

[HTML][HTML] LncRNA NORAD mediates KMT2D expression by targeting miR-204-5p and affects the growth of gastric cancer

X Chen, T Pan, G Guo, G Chen, Y Cai… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background Long non-coding ribonucleic acids (lncRNAs) are a class of non-coding RNAs
implicated in the development of many malignancies, including gastric cancer (GC). In this …

[HTML][HTML] NORAD-Regulated Signaling Pathways in Breast Cancer Progression

AM Capela, C Tavares-Marcos, HF Estima-Arede… - Cancers, 2024 - mdpi.com
Simple Summary Breast cancer (BC) is a heterogeneous disease classified into different
subtypes presenting several treatment challenges, especially in more advanced cases …

Roles of non-coding RNAs in the metabolism and pathogenesis of bladder cancer

DRA Sanya, D Onésime - Human Cell, 2023 - Springer
Bladder cancer (BC) is featured as the second most common malignancy of the urinary tract
worldwide with few treatments leading to high incidence and mortality. It stayed a virtually …

Diagnostic value of lncRNA NORAD in pulmonary tuberculosis and its regulatory role in Mycobacterium tuberculosis infection of macrophages

W Sun, X He, X Zhang, X Wang, W Lin… - Microbiology and …, 2022 - Wiley Online Library
Pulmonary tuberculosis (PTB) infection is a chronic inflammatory response caused by
Mycobacterium tuberculosis (Mtb). The purpose of this study was to confirm the value of long …

miR-155-5p 在肿瘤中的表达, 功能以及调控作用

靳睿哲, 王迪娴, 赵乾, 刘铁军 - 肿瘤防治研究, 2023 - zlfzyj.com
MicroRNA (miRNA) 是一类小的, 单链非编码RNA, 作为与基因表达相关的调控因子参与生命
过程中的一系列重要进程. 目前, 已有大量研究表明miRNA 的表达失调可能是人类肿瘤产生和 …

Construction and identification of lncRNA/circRNA-coregulated ceRNA networks in gemcitabine-resistant bladder carcinoma

J Pan, X Xie, J Sheng, C Ju, S Sun, F Cui… - …, 2023 - academic.oup.com
Objectives To explore the regulatory networks that underlie the development of
chemoresistance in bladder cancer. Methods We analyzed profiles of differentially …

miR-155-5p Expression, Function and Regulation in Tumors

JIN Ruizhe, Z Qian - Cancer Research on Prevention and Treatment, 2023 - zlfzyj.com
MicroRNAs (miRNAs) are a class of small, single-stranded non-coding RNAs that act as
important regulators of gene expression and are involved in a number of important …

[HTML][HTML] The Possible Role of The Long Non-Coding RNA NORAD in Mitomycin C-Related Chemoresistance

İ BOZGEYİK - 2022 - namikkemalmedj.com
Aim: Non-coding ribonucleic acid (RNA) activated by deoxyribonucleic acid (DNA) damage
(NORAD) is a long non-coding RNA activated during DNA damage response. Accumulating …