The study of sophisticated biomaterials and their cellular targets requires visualization
methods with exquisite spatial and temporal resolution to discern cell organelles and …

The basement membrane (BM) provides a physical barrier to invasion in epithelial tumors,
and alterations in the molecular makeup and structural integrity of the BM have been …

During embryonic development, the heart undergoes complex morphogenesis from a liner
tube into the four chambers consisting of ventricles, atria and valves. At the same time, the …

Engineered culture substrates have proven invaluable for investigating the role of cell and
extracellular matrix geometry in governing cell behavior. While the mechanisms relating …

Background Biofunctionalization of titanium surfaces can improve host responses,
especially considering the time for osteointegration and patient recovery. This prompted us …

Mixed polymer brushes (MPBs) consist of a combination of two or more disparate polymers
with one end tethered to an interface by covalent bond and the other end stretched into the …

Engineered, in vitro cardiac cell and tissue systems provide test beds for the study of cardiac
development, cellular disease processes, and drug responses in a dish. Much effort has …

Cells in our body experience different types of stress including compression, tension, and
shear. It has been shown that some cells experience permanent plastic deformation after a …

Astronauts experience significant and rapid bone loss as a result of an extended stay in
space, making the International Space Station (ISS) the perfect laboratory for studying …

Hybrid scaffolds composed of synthetic polymers and naturally occurring components have
become more relevant in the field of tissue engineering and regenerative medicine …