[HTML][HTML] Plant-derived compounds in treatment of leishmaniasis

A Oryan - Iranian journal of veterinary research, 2015 - ncbi.nlm.nih.gov
Leishmaniasis is a neglected public health problem caused by the protozoan species
belonging to the genus Leishmania affecting mostly the poor populations of developing …

Immunotherapy in treatment of leishmaniasis

M Akbari, A Oryan, G Hatam - Immunology Letters, 2021 - Elsevier
Leishmaniasis caused by various species of protozoan transmitted by sand fly vectors
occurs as a spectrum of clinical features including cutaneous, mucocutaneous and visceral …

Natural products: insights into leishmaniasis inflammatory response

IA Rodrigues, AM Mazotto, V Cardoso… - Mediators of …, 2015 - Wiley Online Library
Leishmaniasis is a vector‐borne disease that affects several populations worldwide, against
which there are no vaccines available and the chemotherapy is highly toxic. Depending on …

[HTML][HTML] Identification of some chalcone analogues as potential antileishmanial agents: An integrated in vitro and in silico evaluation

MS Osman, TA Awad, SW Shantier… - Arabian Journal of …, 2022 - Elsevier
Chalcones, either natural or synthetic, are known to exhibit various biological activities. The
present study aimed to evaluate the in vitro and in silico activities of some chalcone …

Green synthesis, antileishmanial activity evaluation, and in silico studies of new amino acid-coupled 1, 2, 4-triazoles

AM El-Saghier, MA Mohamed, OA Abd-Allah… - Medicinal Chemistry …, 2019 - Springer
Candidates of triazole-containing amino acid derivatives 5a− k were prepared under green
chemistry conditions via multicomponent reaction using lemon juice as an acidic catalyst. All …

Nematocidal effects of a coriander essential oil and five pure principles on the infective larvae of major ovine gastrointestinal nematodes in vitro

MA Helal, AM Abdel-Gawad, OM Kandil, MME Khalifa… - Pathogens, 2020 - mdpi.com
The anthelmintic effects of extracted coriander oil and five pure essential oil constituents
(geraniol, geranyl acetate, eugenol, methyl iso-eugenol, and linalool) were tested, using …

Active essential oils and their components in use against neglected diseases and arboviruses

EC Luna, IS Luna, L Scotti… - Oxidative medicine …, 2019 - Wiley Online Library
The term neglected diseases refers to a group of infections caused by various classes of
pathogens, including protozoa, viruses, bacteria, and helminths, most often affecting …

[HTML][HTML] Linalool, a Piper aduncum essential oil component, has selective activity against Trypanosoma cruzi trypomastigote forms at 4°C

LH Villamizar, MG Cardoso, J Andrade… - Memórias do Instituto …, 2017 - SciELO Brasil
BACKGROUND Recent studies showed that essential oils from different pepper species
(Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES In …

Chagas disease: the challenge of polyparasitism?

CJ Perez, AJ Lymbery, RCA Thompson - Trends in parasitology, 2014 - cell.com
The debilitating zoonosis Chagas disease (CD) is caused by infection with the flagellate
protozoan Trypanosoma cruzi. One century after its discovery, a curative agent remains …

Antileishmanial Activity of the Essential Oil from Bixa orellana

L Monzote, M García, R Scull, A Cuellar… - Phytotherapy …, 2014 - Wiley Online Library
Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa. There is
currently no vaccine against leishmaniasis, and chemotherapy remains the only effective …