Personalized medicine: Time for one-person trials | Nature Skip to main content Thank you for
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Asthma exacerbation is a common reason for children to present to the emergency
department. If primary therapies fail to halt the progression of an asthma flare, status …

Summary β-adrenergic receptors (β-ARs), prototypic G-protein-coupled receptors (GPCRs),
play a critical role in regulating numerous physiological processes. The GPCR kinases …

Severe and poorly controlled asthma still accounts for a great portion of the patients affected.
Disease control and future risk management have been identified by international …

Rationale: A significant population of patients with severe asthma and chronic obstructive
pulmonary disease is less responsive to β2-adrenoceptor agonists and corticosteroids, and …

Agonist-dependent activation of G protein-coupled receptors induces diversified receptor
cellular and signaling properties. Norepinephrine (NE) and epinephrine (Epi) are two …

Medical research: Missing patients | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Allergic asthma, a major cause of morbidity and leading cause of hospitalizations, is an
inflammatory disease orchestrated by T helper cells and characterized by the lung migration …

Agonists of β2 adrenergic receptors (β2AR) and glucocorticoid receptors (GR) are
prescribed to treat pulmonary diseases. Since ozone effects are mediated through the …

BACKGROUND: After the Serevent Nationwide Surveillance clinical trial, controversy has
surrounded the safety of long-acting beta agonists (LABAs). OBJECTIVE: Examine the …