The aggregation of a polypeptide chain into amyloid fibrils and their accumulation and
deposition into insoluble plaques and intracellular inclusions is the hallmark of several …

Protein amyloid aggregation is a hallmark in neuropathologies and other diseases of
tremendous impact such as Alzheimer's or Parkinson's diseases. During the last decade, it …

The self-assembly of proteins into fibrillar structures called amyloid fibrils underlies the onset
and symptoms of neurodegenerative diseases, such as Alzheimer's and Parkinson's …

This doctoral thesis investigates the molecular principles of protein misfolding, like
threedimensional domain-swapping or amyloid formation. For this purpose, we have used a …

Trichomonas vaginalis is a flagellated protozoan parasite that causes trichomoniasis, the
world most common non-viral sexually transmitted infection. Although infections may be …

The survival and health of all organisms depend on the ability of their constituent proteins to
fold into precise three-dimensional conformations in order to develop their biological …