Micro-and nanoplastics (MNPs) are recognized as emerging contaminants, especially in
food, with unknown health significance. MNPs passing through the gastrointestinal tract …

A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …

Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate
intracellular signaling cascades that have important consequences for cellular behavior …

Colorectal cancer (CRC) is a leading cause of death in the United States. Despite its slow
development and the capacity for early diagnosis, current preventive approaches are not …

Background Substantial evidence indicates that dysbiosis of the gut microbial community is
associated with colorectal neoplasia. This review aims to systematically summarise the …

Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …

Somatostatin (SS) and urotensin II (UII) are members of two families of structurally related
neuropeptides present in all vertebrates. They exert a large array of biological activities that …

The biological significance of dehydroepiandrosterone (DHEA) which, in the form of its
sulfated ester is the most abundant steroid hormone in human plasma, is an enigma. Over …

Estrogen is a kind of steroid compound that has extensive biologic activities. The effect of
estrogen is pleiotropic, affecting multiple systems in the body. There is accumulating …