Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog Epidermal …
N Tateyama, R Nanamiya, T Ohishi, J Takei… - Monoclonal …, 2021 - liebertpub.com
The epidermal growth factor receptor (EGFR) is a type I transmembrane protein, which is a
member of the human epidermal growth factor receptor (HER) family of receptor tyrosine …
member of the human epidermal growth factor receptor (HER) family of receptor tyrosine …
[HTML][HTML] Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR …
X Liu, S Tian, M Liu, L Jian… - … Journal of Molecular …, 2016 - spandidos-publications.com
The anticancer effects of the natural flavonoid, wogonin, have been reported. However, its
molecular mechanisms of action have not yet been fully explored. In the present study, we …
molecular mechanisms of action have not yet been fully explored. In the present study, we …
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines
L Zhang, J Li, J Hu, D Li, X Wang, R Zhang, H Zhang… - Lung Cancer, 2017 - Elsevier
Objectives Epithelial growth factor receptor (EGFR) somatic-mutated non-small cell lung
cancer (NSCLC) patients with smoking history always show a poor response to EGFR …
cancer (NSCLC) patients with smoking history always show a poor response to EGFR …
Combination of two miRNAs has a stronger effect on stimulating apoptosis, inhibiting cell growth, and increasing erlotinib sensitivity relative to single miRNA in A549 …
J Amri, N Molaee, H Karami… - … and Applied Biochemistry, 2022 - Wiley Online Library
Despite the dramatic efficacy of EGFR‐TKIs, most of non‐small cell lung cancer patients
ultimately develop resistance to these agents. In this study, we explored the effects of miRNA …
ultimately develop resistance to these agents. In this study, we explored the effects of miRNA …
[HTML][HTML] ZNF32 contributes to the induction of multidrug resistance by regulating TGF-β receptor 2 signaling in lung adenocarcinoma
J Li, J Ao, K Li, J Zhang, Y Li, L Zhang, Y Wei… - Cell death & …, 2016 - nature.com
Multidrug resistance (MDR) is one of the most important contributors to the high mortality of
cancer and remains a major concern. We previously found that zinc finger protein 32 …
cancer and remains a major concern. We previously found that zinc finger protein 32 …
Quantification of HER family dimers by proximity ligation assay and its clinical evaluation in non–small cell lung cancer patients treated with osimertinib
R Liu, K Ota, E Iwama, Y Yoneshima, K Tanaka… - Lung Cancer, 2021 - Elsevier
Objectives The epidermal growth factor receptor (EGFR, also known as Her1) is a member
of the human epidermal growth factor receptor (HER) family of proteins and a target of …
of the human epidermal growth factor receptor (HER) family of proteins and a target of …
[HTML][HTML] A novel EGFR-TKI inhibitor (cAMP-H3BO3complex) combined with thermal therapy is a promising strategy to improve lung cancer treatment outcomes
Y Tong, C Huang, J Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Purpose Although EGFR-TKIs (epidermal growth factor receptor tyrosine kinase inhibitors)
induce favorable responses as first-line non-small cell lung cancer treatments, drug …
induce favorable responses as first-line non-small cell lung cancer treatments, drug …
[HTML][HTML] Azd9291 inhibitor
J Amri, N Molaee, H Karami, M Baazm - azd9291inhibitor.com
Despite the dramatic efficacy of EGFR-TKIs, most of non-small cell lung cancer patients
ultimately develop resistance to these agents. In this study, we explored the effects of miRNA …
ultimately develop resistance to these agents. In this study, we explored the effects of miRNA …
Clinical approach of intratumoral heterogeneity in lung adenocarcinoma. Two clinical cases with changing somatic driver mutations
M Saigi, C Gilson, H Rush, R Lal - Cancer Treatment and Research …, 2016 - Elsevier
Cancer is a dynamic process of somatic evolution. Distinct cell populations that undergo
mutations, result in positive or negative selection depending on whether or not these …
mutations, result in positive or negative selection depending on whether or not these …