Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

Viruses causing chronic infection artfully manipulate infected cells to enable viral
persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 …

Adult T-cell leukemia/lymphoma (ATL) is a highly aggressive T-cell malignancy that arises in
a proportion of individuals who are long-term carriers of human T-lymphotropic virus type 1 …

Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

Chronic infection is one of the major causes of cancer, and there are several mechanisms
for infection‐mediated oncogenesis. Some pathogens encode gene products that behave …

Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus which mainly infects CD4+ T cells
and causes adult T-cell leukemia/lymphoma (ATL), is primarily transmitted via direct cell-to …

Human T Lymphotropic virus (HTLV) infection can persist in individuals resulting, at least in
part, from viral escape of the innate immunity, including inhibition of type I interferon …

HTLV-1 orf-I is linked to immune evasion, viral replication and persistence. Examining the orf-
I sequence of 160 HTLV-1-infected individuals; we found polymorphism of orf-I that alters the …

Background The role of innate immunity in general and of type I interferon (IFN-I) in
particular in HTLV-1 pathogenesis is still a matter of debate. ADAR1-p150 is an Interferon …