Advances and future perspectives of intranasal drug delivery: A scientometric review

D Xu, XJ Song, X Chen, JW Wang, YL Cui - Journal of Controlled Release, 2024 - Elsevier
Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

A review of coformer utilization in multicomponent crystal formation

N Wathoni, WA Sari, KM Elamin, AFA Mohammed… - Molecules, 2022 - mdpi.com
Most recently discovered active pharmaceutical molecules and market-approved medicines
are poorly soluble in water, resulting in limited drug bioavailability and therapeutic …

Virtual multicomponent crystal screening: Hydrogen bonding revisited

S Ahmadi, PK Mondal, Y Wu, W Gong… - Crystal Growth & …, 2021 - ACS Publications
Pharmaceutical cocrystals, salts, and multicomponent crystals, in general, have increasingly
come under the spotlight in recent years. A fast and efficient a priori theoretical classifier to …

Pharmaceutical cocrystals and salts of enrofloxacin: Structure and properties

SY Yang, FK Zhao, H Pang, LZ Chen, RB Shi… - Journal of Molecular …, 2022 - Elsevier
Enrofloxacin, a second-generation quinolone broad-spectrum antimicrobial, has limited
application because of its poor solubility. The purpose of this paper was to investigate the …

Enantiotropic inconstancy, crystalline solid solutions and co-crystal in the salicylic acid–anthranilic acid system

FL Nordstrom, SS Mohajerani, B Linehan… - Physical Chemistry …, 2022 - pubs.rsc.org
The phase boundaries and thermodynamic properties of crystal phases in the salicylic acid
(SA)–anthranilic acid (AA) system have been determined experimentally. The complete …

Recent patents of pharmaceutical co-crystals: product development on anti-cancer drugs and beyond

AA Tharik, SN Meyyanathan - Recent Patents on Anti-Cancer …, 2023 - ingentaconnect.com
Background: Scientists, academicians, and researchers from academics and the
pharmaceutical industries have all expressed interest in the design and production of …

Structural aspects, solid-state properties, and solubility performance of pharmaceutical sertraline-based organic salts

LF Diniz, JC Tenorio, C Ribeiro… - Journal of Molecular …, 2023 - Elsevier
Salt formation has been a traditional and successful strategy in modulating the
biopharmaceutical physicochemical properties of the active pharmaceutical compound …

Combined virtual and experimental screening of multicomponent crystals of 2, 4-dichlorophenoxyacetic acid

J Li, C Li, X Ji, Q Sun, Z Li, H Liu, L Zhou… - New Journal of …, 2022 - pubs.rsc.org
2, 4-Dichlorophenoxyacetic acid (2, 4-D) is an herbicide and plant growth regulator that is
widely applied in crop production. New multicomponent crystals of 2, 4-D have been …

Utilization of polymeric micelles as a lucrative platform for efficient brain deposition of olanzapine as an antischizophrenic drug via intranasal delivery

HA Abo El-Enin, MF Ahmed, IA Naguib, SW El-Far… - Pharmaceuticals, 2022 - mdpi.com
Schizophrenia is a mental disorder characterized by alterations in cognition, behavior and
emotions. Oral olanzapine (OZ) administration is extensively metabolized (~ up to 40% of …

Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile

C Fandaruff, MI Quirós-Fallas, JR Vega-Baudrit… - Pharmaceutics, 2023 - mdpi.com
The dissolution rate of the anti-HIV drug saquinavir base (SQV), a poorly water-soluble and
extremely low absolute bioavailability drug, was improved through a eutectic mixture …