[PDF][PDF] The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

[HTML][HTML] Improving the study of brain-behavior relationships by revisiting basic assumptions

C Westlin, JE Theriault, Y Katsumi… - Trends in cognitive …, 2023 - cell.com
Neuroimaging research has been at the forefront of concerns regarding the failure of
experimental findings to replicate. In the study of brain-behavior relationships, past failures …

The secret life of predictive brains: what's spontaneous activity for?

G Pezzulo, M Zorzi, M Corbetta - Trends in cognitive sciences, 2021 - cell.com
Brains at rest generate dynamical activity that is highly structured in space and time. We
suggest that spontaneous activity, as in rest or dreaming, underlies top-down dynamics of …

[HTML][HTML] Subcortical-cortical dynamical states of the human brain and their breakdown in stroke

C Favaretto, M Allegra, G Deco, NV Metcalf… - Nature …, 2022 - nature.com
The mechanisms controlling dynamical patterns in spontaneous brain activity are poorly
understood. Here, we provide evidence that cortical dynamics in the ultra-slow frequency …

[HTML][HTML] Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice

AM Rosenberg, M Saggar, AS Monzel, J Devine… - Nature …, 2023 - nature.com
The brain and behavior are under energetic constraints, limited by mitochondrial energy
transformation capacity. However, the mitochondria-behavior relationship has not been …

Imaging whole-brain activity to understand behaviour

A Lin, D Witvliet, L Hernandez-Nunez… - Nature Reviews …, 2022 - nature.com
Until now, most brain studies have focused on small numbers of neurons that interact in
limited circuits, allowing analysis of individual computations or steps of neural processing …

Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes

S Aimon, KY Cheng, J Gjorgjieva, ICG Kadow - Elife, 2023 - elifesciences.org
This paper expands on prior work by using whole-brain calcium imaging in Drosophila to
examine how spontaneous and forced walking and turning affect neural activity in the brain …

Lactate supply overtakes glucose when neural computational and cognitive loads scale up

Y Dembitskaya, C Piette, S Perez… - Proceedings of the …, 2022 - National Acad Sciences
Neural computational power is determined by neuroenergetics, but how and which energy
substrates are allocated to various forms of memory engram is unclear. To solve this …

[HTML][HTML] Fast, efficient, and accurate neuro-imaging denoising via supervised deep learning

S Chaudhary, S Moon, H Lu - Nature communications, 2022 - nature.com
Volumetric functional imaging is widely used for recording neuron activities in vivo, but there
exist tradeoffs between the quality of the extracted calcium traces, imaging speed, and laser …

[HTML][HTML] The spatial and temporal structure of neural activity across the fly brain

ES Schaffer, N Mishra, MR Whiteway, W Li… - Nature …, 2023 - nature.com
What are the spatial and temporal scales of brainwide neuronal activity? We used swept,
confocally-aligned planar excitation (SCAPE) microscopy to image all cells in a large …