[HTML][HTML] Non-viral vectors in gene therapy: recent development, challenges, and prospects
H Zu, D Gao - The AAPS journal, 2021 - Springer
Gene therapy has been experiencing a breakthrough in recent years, targeting various
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …
[HTML][HTML] Progress in mesoporous silica nanoparticles as drug delivery agents for cancer treatment
Cancer treatment and therapy have made significant leaps and bounds in these past
decades. However, there are still cases where surgical removal is impossible, metastases …
decades. However, there are still cases where surgical removal is impossible, metastases …
[HTML][HTML] Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications
Rapid progress in developing multifunctional nanocarriers for drug delivery has been
observed in recent years. Inorganic mesoporous silica nanocarriers (MSNs), emerged as an …
observed in recent years. Inorganic mesoporous silica nanocarriers (MSNs), emerged as an …
Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery
Inorganic mesoporous silica nanoparticles (MSN) are porous materials extensively studied
for drug delivery due to their properties such as facile and diverse synthesis methods …
for drug delivery due to their properties such as facile and diverse synthesis methods …
Engineered mesoporous silica nanoparticles, new insight nanoplatforms into effective cancer gene therapy
The use of nucleic acid to control the expression of genes relevant to tumor progression is a
key therapeutic approach in cancer research. Therapeutics based on nucleic acid provide …
key therapeutic approach in cancer research. Therapeutics based on nucleic acid provide …
Nonviral nanoparticle gene delivery into the CNS for neurological disorders and brain cancer applications
Nonviral nanoparticles have emerged as an attractive alternative to viral vectors for gene
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …
Advances in regulating physicochemical properties of mesoporous silica nanocarriers to overcome biological barriers
Y Wang, K Gou, X Guo, J Ke, S Li, H Li - Acta Biomaterialia, 2021 - Elsevier
Mesoporous silica nanoparticles (MSNs) with remarkable structural features have been
proven to be an excellent platform for the delivery of therapeutic molecules. Biological …
proven to be an excellent platform for the delivery of therapeutic molecules. Biological …
[HTML][HTML] Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy
K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
Natural prodrugs derived from different natural origins (eg, medicinal plants, microbes,
animals) have a long history in traditional medicine. They exhibit a broad range of …
animals) have a long history in traditional medicine. They exhibit a broad range of …
[HTML][HTML] Recent advances in mesoporous silica nanoparticle-mediated drug delivery for breast cancer treatment
R Rani, P Malik, S Dhania, TK Mukherjee - Pharmaceutics, 2023 - mdpi.com
Breast cancer (BC) currently occupies the second rank in cancer-related global female
deaths. Although consistent awareness and improved diagnosis have reduced mortality in …
deaths. Although consistent awareness and improved diagnosis have reduced mortality in …
Challenges for the application of EGFR-targeting peptide GE11 in tumor diagnosis and treatment
T Hailing, P Yonghong, Z Yufeng, T Haitao - Journal of Controlled Release, 2022 - Elsevier
Abnormal regulation of cell signaling pathways on cell survival, proliferation and migration
contributes to the development of malignant tumors. Among them, epidermal growth factor …
contributes to the development of malignant tumors. Among them, epidermal growth factor …