[HTML][HTML] Critical power: an important fatigue threshold in exercise physiology

DC Poole, M Burnley, A Vanhatalo… - Medicine and science …, 2016 - ncbi.nlm.nih.gov
The hyperbolic form of the power-duration relationship is rigorous and highly conserved
across species, forms of exercise and individual muscles/muscle groups. For modalities …

Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs

MJ Joyner, DP Casey - Physiological reviews, 2015 - journals.physiology.org
This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Muscle satellite cell cross-talk with a vascular niche maintains quiescence via VEGF and notch signaling

M Verma, Y Asakura, BSR Murakonda, T Pengo… - Cell stem cell, 2018 - cell.com
Skeletal muscle is a complex tissue containing tissue resident muscle stem cells (satellite
cells)(MuSCs) important for postnatal muscle growth and regeneration. Quantitative analysis …

Identification of novel sublingual parameters to analyze and diagnose microvascular dysfunction in sepsis: the NOSTRADAMUS study

A Rovas, J Sackarnd, J Rossaint, S Kampmeier… - Critical Care, 2021 - Springer
Background The availability of handheld, noninvasive sublingual video-microscopes allows
for visualization of the microcirculation in critically ill patients. Recent studies demonstrate …

Exercise training in chronic heart failure: improving skeletal muscle O2 transport and utilization

DM Hirai, TI Musch, DC Poole - American Journal of …, 2015 - journals.physiology.org
Chronic heart failure (CHF) impairs critical structural and functional components of the O2
transport pathway resulting in exercise intolerance and, consequently, reduced quality of …

Blood flow, capillary transit times, and tissue oxygenation: the centennial of capillary recruitment

L Østergaard - Journal of Applied Physiology, 2020 - journals.physiology.org
The transport of oxygen between blood and tissue is limited by blood's capillary transit time,
understood as the time available for diffusion exchange before blood returns to the heart. If …

Exercise limitations in heart failure with reduced and preserved ejection fraction

DC Poole, RS Richardson… - Journal of applied …, 2018 - journals.physiology.org
The hallmark symptom of chronic heart failure (HF) is severe exercise intolerance. Impaired
perfusive and diffusive O2 transport are two of the major determinants of reduced physical …

Critical power is positively related to skeletal muscle capillarity and type I muscle fibers in endurance-trained individuals

EA Mitchell, NRW Martin, SJ Bailey… - Journal of Applied …, 2018 - journals.physiology.org
The asymptote [critical power (CP)] and curvature constant (W′) of the hyperbolic power-
duration relationship can predict performance within the severe-intensity exercise domain …

The role of vascular function on exercise capacity in health and disease

DC Poole, BJ Behnke, TI Musch - The Journal of physiology, 2021 - Wiley Online Library
Three sentinel parameters of aerobic performance are the maximal oxygen uptake (), critical
power (CP) and speed of the kinetics following exercise onset. Of these, the latter is …

August Krogh's theory of muscle microvascular control and oxygen delivery: a paradigm shift based on new data

DC Poole, RN Pittman, TI Musch… - The Journal of …, 2020 - Wiley Online Library
August Krogh twice won the prestigious international Steegen Prize, for nitrogen metabolism
(1906) and overturning the concept of active transport of gases across the pulmonary …