Flow cytometric analysis of cell‐surface and intracelluar antigens in leukemia diagnosis

W Knapp, H Strobl, O Majdic - Cytometry: The Journal of the …, 1994 - Wiley Online Library
New technology allows highly sensitive flow cytometric detection and quantitative analysis of
intracellular antigens in normal and malignant hemopoietic cells. With this technology, the …

AML1 Interconnected Pathways of Leukemogenesis: MOLECULAR BIOLOGY AND GENETICS

J Michaud, HS Scott, R Escher - Cancer investigation, 2003 - Taylor & Francis
The AML1 transcription factor, identified by the cloning of the translocation t (8; 21)
breakpoint, is one of the most frequent targets for chromosomal translocations in leukemia …

Use of the polymerase chain reaction in the detection of A ML1/ETO fusion transcript in t(8;21)

YL Kwong, V Chan, KF Wong, TK Chan - Cancer, 1995 - Wiley Online Library
Abstract Background. t (8; 21)(q22; q22), found in acute myeloid leukemia (AML) and
occasionally in myelodysplasia (MDS), results in the fusion of the AML1 gene on 22q22 to …

Adult patients with t (8; 21) acute myeloid leukemia had no superior treatment outcome to those without t (8; 21): a single institution's experience

KW Lee, IS Choi, EY Roh, DY Kim, T Yun, DS Lee… - Annals of …, 2004 - Springer
Clinical features and treatment outcome of 31 patients over 16 years of age with t (8; 21)
acute myeloid leukemia (AML) were compared with 60 patients without t (8; 21). Among 31 …

Hematological features and treatment outcome in acute myeloid leukemia with t (8; 21)

SK Ma, WY Au, YL Kwong, CK Lam… - Hematological …, 1997 - Wiley Online Library
We analyzed the hematological features and treatment outcome in 18 patients with t (8; 21)
acute myeloid leukemia (AML) diagnosed in Queen Mary Hospital, Hong Kong. They …

[PDF][PDF] 伴t (8; 21)/AML1-ETO 阳性的儿童急性髓系白血病的临床特点及预后研究

吴珺, 张乐萍, 陆爱东, 王彬, 程翼飞, 刘桂兰 - 中国当代儿科杂志, 2011 - zgddek.com
目的分析伴t (8; 21)/AML1 ETO 阳性的儿童急性髓系白血病(AML) 的临床特点,
生物学特征及预后. 方法对伴t (8; 21)/AML1 ETO 阳性的55 例AML 患儿的临床资料进行回顾 …

Persistence of AML1 rearrangement in peripheral blood cells in t (8; 21)

YL Kwong, KF Wong, V Chan, CH Chan - Cancer genetics and cytogenetics, 1996 - Elsevier
Translocation (8; 21)(g22; g22) involves fusion of the AML1 gene with the ETO gene,
generating an AML1/ETO fusion transcript that can be detected by the polymerase chain …

Translocation (3; 21; 8)(q21; q22; q22) in a patient with acute myeloid leukemia: a case report and review of prognostic indicators

FJ Giles, TJ Kanemaki, RR Schreck, L Qasabian… - Cancer genetics and …, 1998 - Elsevier
We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

A variant t (8; 10; 21) in a patient with pathological features mimicking atypical chronic myeloid leukemia

J Lee, WF Kern, JB Cain, JJ Mulvihill, S Li - Cancer genetics and …, 2005 - Elsevier
We report the case of an 11-year-old girl who was initially diagnosed with a chronic
myeloproliferative disorder, possibly chronic myelogenous leukemia (CML), based on …

[引用][C] 应用RT/PCR 技术检测急性粒细胞白血病M2 型AML1/ETO 融合基因转录本的研究

雷平冲, 刘慧娟, 瞿亚萍 - 中国优生与遗传杂志, 2000