The virtues and vices of protein citrullination

MA Christophorou - Royal Society Open Science, 2022 - royalsocietypublishing.org
The post-translational modification of proteins expands the regulatory scope of the proteome
far beyond what is achievable through genome regulation. The field of protein citrullination …

[HTML][HTML] Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis

AJ Shih, RP Adelson, H Vashistha, H Khalili, A Nayyar… - BMC medicine, 2022 - Springer
Background Endometriosis is a common, complex disorder which is underrecognized and
subject to prolonged delays in diagnosis. It is accompanied by significant changes in the …

Peptidylarginine deiminase enzymes and citrullinated proteins in female reproductive physiology and associated diseases

AO Christensen, G Li, CH Young, B Snow… - Biology of …, 2022 - academic.oup.com
Citrullination, the post-translational modification of arginine residues, is catalyzed by the four
catalytically active peptidylarginine deiminase (PAD or PADI) isozymes and alters charge to …

[HTML][HTML] When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments

V Unfer, E Kandaraki, L Pkhaladze, S Roseff… - … and Metabolic Science, 2024 - Elsevier
Abstract Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects a
large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been a …

[HTML][HTML] Transcriptome Analysis of the Ovaries of Taihe Black-Bone Silky Fowls at Different Egg-Laying Stages

X Xiang, X Huang, J Wang, H Zhang, W Zhou, C Xu… - Genes, 2022 - mdpi.com
The poor egg-laying performance and short peak egg-laying period restrict the economic
benefits of enterprises relating to the Taihe black-bone silky fowl. Ovaries are the main …

Effect mono-ADP-ribosylation on lipid metabolism of colorectal cancer by regulating IGFBP1 methylation

CL Wang, Y Tang, SX Zhang, M Xiao, M Li, L Yang… - 2023 - researchsquare.com
In the global health community, colon cancer (CRC) is a major concern, with a high rate of
incidence. Epigenetics is recognized as one of the causes of CRC development and …