Schizophrenia is a psychiatric disorder characterised by symptoms in three domains:
positive (eg delusions, hallucinations), negative (eg social withdrawal, lack of motivation) …

The regulated exocytosis that mediates chemical signaling at synapses requires
mechanisms to coordinate the immediate response to stimulation with the recycling needed …

Neuropsychiatric disorders, including depression, anxiety, schizophrenia, and Alzheimer's
disease (AD), are diseases that are directly or indirectly associated with cerebral dysfunction …

D-amino acids have been known to exist in the human brain for nearly 40 years, and they
continue to be a field of active study to today. This review article aims to give a concise …

Cognitive impairment is a core feature of patients with neuropsychiatric diseases such as
schizophrenia and psychotic depression. The drugs currently used to treat cognitive …

Current treatments for schizophrenia, although effective for positive symptoms, have not
proven as effective for negative symptoms and cognitive dysfunction. Additional strategies …

Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders that pose
important challenges for diagnosis by sharing common symptoms, such as delusions and …

2004/0026364 A1 2/2004 Kihara WO WO 2004/096761 11, 2004 2005, 0124627 A1 6, 2005
Schadt et al. WO WO 2004/110149 12, 2004 2005/0153963 A1 7/2005 Dargazanli et al. WO …

Glial cells consisting of oligodendrocytes, astrocytes, microglia, and NG2 positive cells are
major cell populations in the central nervous system, number-wise. They function as …

Antipsychotic drugs for the treatment of schizophrenia arrived in the clinic in the fifties of the
previous century and have since been the most effective treatment for patients with this …