Ameliorative effect of curcumin on lead‐induced hematological and hepatorenal toxicity in a rat model

K Abubakar, MM Mailafiya, SM Chiroma… - … of Biochemical and …, 2020 - Wiley Online Library
Abstract Introduction Lead (Pb) is a ubiquitous toxic heavy metal that inflicts numerous
clinical consequences on humans. Curcumin is the principal component of turmeric, which is …

Oxidative stress markers and histological analysis in diverse organs from rats treated with a hepatotoxic dose of Cr (VI): effect of curcumin

WR García-Niño, ZL Zatarain-Barrón… - Biological trace element …, 2015 - Springer
Abstract Hexavalent chromium [Cr (VI)] compounds are extremely toxic and carcinogenic.
Despite the vast quantity of reports about Cr (VI) toxicity, the information regarding its effects …

Curcumin pretreatment protects against PM2. 5‑induced oxidized low‑density lipoprotein‑mediated oxidative stress and inflammation in human microvascular …

J Shi, H Deng, M Zhang - Molecular Medicine Reports, 2017 - spandidos-publications.com
A previous study demonstrated that particulate matter (≤ 2.5 µm in diameter; PM2. 5) may
promote atherosclerosis. However, the underlying mechanisms of PM2. 5 in human …

Therapeutic effect of curcumin on 5/6Nx hypertriglyceridemia: association with the improvement of renal mitochondrial β-oxidation and lipid metabolism in kidney and …

ZA Ceja-Galicia, FE García-Arroyo, OE Aparicio-Trejo… - Antioxidants, 2022 - mdpi.com
Chronic kidney disease (CKD) prevalence is constantly increasing, and dyslipidemia in this
disease is characteristic, favoring cardiovascular events. However, the mechanisms of CKD …

Sulforaphane protects from kidney damage during the release of unilateral ureteral obstruction (RUUO) by activating nuclear factor erythroid 2-related factor 2 (Nrf2) …

AK Aranda-Rivera, A Cruz-Gregorio… - Free Radical Biology …, 2024 - Elsevier
Releasing unilateral ureteral obstruction (RUUO) is the gold standard for decreasing renal
damage induced during unilateral ureteral obstruction (UUO); however, the complete …

[HTML][HTML] Advancements in nanomedicines for the detection and treatment of diabetic kidney disease

L Tillman, TA Tabish, N Kamaly, P Moss… - Biomaterials and …, 2022 - Elsevier
In the diabetic kidneys, morbidities such as accelerated ageing, hypertension and
hyperglycaemia create a pro-inflammatory microenvironment characterised by extensive …

Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response

X Chen, J Liu, S Chen - Reproductive Toxicology, 2013 - Elsevier
Nuclear factor erythroid 2-related factor (Nrf2) is a key transcription factor that regulates
antioxidant defense in cells. In this study, we investigated whether over-expression of Nrf2 …

Low-dose lipopolysaccharide protects nerve cells against spinal cord injury via regulating the PI3K–AKT–Nrf2 signaling pathway

WC Li, SP Yao, J Zhang, WB Liu, J Liu… - Biochemistry and Cell …, 2021 - cdnsciencepub.com
This study explored the molecular mechanism behind the protective effects from low-dose
lipopolysaccharide (LPS) on an in-vitro model of spinal cord injury (SCI). For this, PC12 cells …

Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams–Beuren Syndrome Mice by Regulation of MAPK Pathway …

P Ortiz-Romero, A González-Simón, G Egea… - Frontiers in …, 2021 - frontiersin.org
Williams–Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by
a distinctive cognitive phenotype for which there are currently no effective treatments. We …

Effect of curcumin dietary supplementation on growth performance, physiology, carcass characteristics and meat quality in lambs

H Marcon, CF Souza, MD Baldissera, DF Alba… - Annals of Animal …, 2021 - sciendo.com
♦ Corresponding author: aleksandro_ss@ yahoo. com. br abstract this study evaluated the
effects of curcumin dietary supplementation on growth, physiology, carcass characteristics …