The detrusor smooth muscle is the main muscle component of the urinary bladder wall. Its
ability to contract over a large length interval and to relax determines the bladder function …

The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

Biomaterials play a critical role in the engineering of new functional genitourinary tissues for
the replacement of lost or malfunctioning tissues. They provide a temporary scaffolding to …

Objectives. To determine whether a naturally derived collagen-based tissue substitute
developed for urethral reconstruction would be suitable for urethral repair in an animal …

There are a number of conditions of the bladder that can lead to loss of function. Many of
these require reconstructive procedures. However, current techniques may lead to a number …

The growing interest in scaffolding design and increasing research programs dedicated to
regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While …

Cell growth supports (ie, scaffolds) that provide a conducive environment for normal cellular
growth, differentiation, and angiogenesis are important components of tissue engineered …

In this study, we compared four decellularization protocols and finally developed an
optimized one through which a porcine bladder acellular matrix (BAM) with well-preserved …

Applications of regenerative medicine technology may offer novel therapies for patients with
injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from …

Novel therapies resulting from regenerative medicine and tissue engineering technology
may offer new hope for patients with injuries, end-stage organ failure, or other clinical …