Maintaining skeletal muscle function throughout the lifespan is a prerequisite for good health
and independent living. For skeletal muscle to consistently function at optimal levels, the …

MicroRNAs (miRNA) are short (∼ 22 nucleotides) non-coding RNA molecules that regulate
gene expression at the post-transcriptional level. Their expression is specific to cells and …

Aims/hypothesis MicroRNAs regulate a broad range of biological mechanisms. To
investigate the relationship between microRNA expression and type 2 diabetes, we …

Cardiac and skeletal muscle development are controlled by evolutionarily conserved
networks of transcription factors that coordinate the expression of genes involved in muscle …

MicroRNAs negatively regulate gene expression by promoting mRNA degradation and
inhibiting mRNA translation. Recent studies have uncovered a cadre of muscle-specific …

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNA species involved
in post-transcriptional gene regulation. In vitro studies have identified a small number of …

When human skeletal muscle is exposed to exercise training, the outcomes, in terms of
physiological adaptation, are unpredictable. The significance of this fact has long been …

In recent years, microRNAs have been shown to play important roles in physiological as well
as malignant processes. The PhenomiR database http://mips. helmholtz-muenchen …

Dystrophin absence in Duchenne muscular dystrophy (DMD) causes severe muscle
degeneration. We describe that, as consequence of fibre damage, specific muscle‐miRNAs …

Objective: Facioscapulohumeral muscular dystrophy (FSHD) is associated with D4Z4 repeat
contraction on human chromosome 4q35. This genetic lesion does not result in complete …