MicroRNAs (miRNAs, miRs) modulate a multitude of cellular events. Here, we identify
functional miRNA-protein networks that regulate human monocyte-derived dendritic cell …

MicroRNAs represent a class of small RNAs derived from polymerase II controlled
transcriptional regions. The primary transcript forms one or several bulging double stranded …

Multiple microRNAs are known to be induced during the differentiation of myoblasts to
myotubes. Yet, experiments in animals have not provided clear evidence for the requirement …

MicroRNAs (MiRNAs) belong to a class of small non‐coding regulatory RNAs that act
through repression of protein expression at post‐transcriptional level and emerge to play …

Sarcopenia, skeletal muscle loss during aging, is associated with increased falls, fractures,
morbidity, and loss of independence. MicroRNAs (miRNAs) are novel posttranscriptional …

Background Skeletal muscle insulin resistance (IR) is considered a critical component of
type II diabetes, yet to date IR has evaded characterization at the global gene expression …

Skeletal muscle mitochondrial dysfunction is believed to play a role in the progression and
severity of amyotrophic lateral sclerosis (ALS). The regulation of transcriptional co-activators …

It has recently been established that exosomes can mediate intercellular cross-talk under
normal and pathological conditions through the transfer of specific miRNAs. As muscle cells …

Chronic kidney disease (CKD) accelerates muscle protein degradation by stimulating the
ubiquitin proteasome system through activation of the E3 ligases, Atrogin-1/MAFbx and …

In Duchenne muscular dystrophy (DMD) the absence of dystrophin at the sarcolemma
delocalizes and downregulates nitric oxide synthase (nNOS); this alters S-nitrosylation of …