Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy

TC Roberts, KEM Blomberg, G McClorey… - … Therapy-Nucleic Acids, 2012 - cell.com
MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are
implicated in wide-ranging cellular processes and pathological conditions including …

microRNAs and muscle disorders

JF Chen, TE Callis, DZ Wang - Journal of cell science, 2009 - journals.biologists.com
MicroRNAs (miRNAs) are a class of non-coding regulatory RNAs of∼ 22 nucleotides in
length. miRNAs are highly conserved across a number of species, including plants, worms …

An estrogen receptor α suppressor, microRNA‐22, is downregulated in estrogen receptor α‐positive human breast cancer cell lines and clinical samples

J Xiong, D Yu, N Wei, H Fu, T Cai, Y Huang… - The FEBS …, 2010 - Wiley Online Library
Previous studies have suggested that microRNAs (miRNAs) may play important roles in
tumorigenesis, but little is known about the functions of most miRNAs in cancer …

MEF2A regulates the Gtl2-Dio3 microRNA mega-cluster to modulate WNT signaling in skeletal muscle regeneration

CM Snyder, AL Rice, NL Estrella, A Held… - …, 2013 - journals.biologists.com
Understanding the molecular mechanisms of skeletal muscle regeneration is crucial to
exploiting this pathway for use in tissue repair. Our data demonstrate that the MEF2A …

A potential role for intragenic miRNAs on their hosts' interactome

LCG Hinske, PAF Galante, WP Kuo, L Ohno-Machado - BMC genomics, 2010 - Springer
Background miRNAs are small, non-coding RNA molecules that mainly act as negative
regulators of target gene messages. Due to their regulatory functions, they have lately been …

Distinct expression of muscle‐specific microRNAs (myomirs) in brown adipocytes

TB Walden, JA Timmons, P Keller… - Journal of cellular …, 2009 - Wiley Online Library
MicroRNAs, a novel class of post‐transcriptional gene regulators, have been demonstrated
to be involved in several cellular processes regulating the expression of protein‐coding …

Compromised autophagy by MIR30Bbenefits the intracellular survival of Helicobacter pylori

B Tang, N Li, J Gu, Y Zhuang, Q Li, HG Wang, Y Fang… - Autophagy, 2012 - Taylor & Francis
Helicobacter pylori evade immune responses and achieve persistent colonization in the
stomach. However, the mechanism by which H. pylori infections persist is not clear. In this …

MicroRNAs in skeletal muscle biology and exercise adaptation

TJ Kirby, JJ McCarthy - Free radical biology and medicine, 2013 - Elsevier
MicroRNAs (miRNAs) have emerged as important players in the regulation of gene
expression, being involved in most biological processes examined to date. The proposal …

miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4

KP Lee, YJ Shin, AC Panda… - Genes & …, 2015 - genesdev.cshlp.org
The myogenic capacity of myoblasts decreases in skeletal muscle with age. In addition to
environmental factors, intrinsic factors are important for maintaining the regenerative …

Defective homocysteine metabolism: potential implications for skeletal muscle malfunction

S Veeranki, SC Tyagi - International journal of molecular sciences, 2013 - mdpi.com
Hyperhomocysteinemia (HHcy) is a systemic medical condition and has been attributed to
multi-organ pathologies. Genetic, nutritional, hormonal, age and gender differences are …