NF-kappaB signaling pathways in neurological inflammation: a mini review
RH Shih, CY Wang, CM Yang - Frontiers in molecular neuroscience, 2015 - frontiersin.org
The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …
NF-κB in the nervous system
B Kaltschmidt, C Kaltschmidt - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
The transcription factor NF-κB has diverse functions in the nervous system, depending on
the cellular context. NF-κB is constitutively activated in glutamatergic neurons. Knockout of …
the cellular context. NF-κB is constitutively activated in glutamatergic neurons. Knockout of …
Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients
JS Rao, VL Keleshian, S Klein, SI Rapoport - Translational psychiatry, 2012 - nature.com
Alzheimer's disease (AD) and bipolar disorder (BD) are progressive brain disorders.
Upregulated mRNA and protein levels of neuroinflammatory and arachidonic acid (AA) …
Upregulated mRNA and protein levels of neuroinflammatory and arachidonic acid (AA) …
The IKK‐NF‐κB pathway: a source for novel molecular drug targets in pain therapy?
E Niederberger, G Geisslinger - The FASEB Journal, 2008 - Wiley Online Library
Several studies indicate that the nuclear factor‐kappa B (NF‐κB)‐activation cascade plays a
crucial role not only in immune responses, inflammation, and apoptosis but also in the …
crucial role not only in immune responses, inflammation, and apoptosis but also in the …
NF-KappaB in long-term memory and structural plasticity in the adult mammalian brain
B Kaltschmidt, C Kaltschmidt - Frontiers in molecular neuroscience, 2015 - frontiersin.org
The transcription factor nuclear factor kappaB (NF-κB) is a well-known regulator of
inflammation, stress, and immune responses as well as cell survival. In the nervous system …
inflammation, stress, and immune responses as well as cell survival. In the nervous system …
IL-1β induced cytokine expression by spinal astrocytes can play a role in the maintenance of chronic inflammatory pain
A Gajtkó, E Bakk, K Hegedűs, L Ducza… - Frontiers in …, 2020 - frontiersin.org
It is now widely accepted that the glial cells of the central nervous system (CNS) are key
players in many processes, especially when they are activated via neuron-glia or glia-glia …
players in many processes, especially when they are activated via neuron-glia or glia-glia …
Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation
JE Hartung, O Eskew, T Wong, IE Tchivileva… - Brain, behavior, and …, 2015 - Elsevier
Nuclear factor-kappa B (NF-κB) is a ubiquitously expressed protein complex regulating the
transcription of genes involved in inflammation and pain. Increased NF-κB activity in immune …
transcription of genes involved in inflammation and pain. Increased NF-κB activity in immune …
The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1. 7 in DRG neurons of rats with diabetic neuropathy
Y Huang, Y Zang, L Zhou, W Gui, X Liu… - Neurochemistry …, 2014 - Elsevier
Diabetic neuropathy (DN) is a common form of peripheral neuropathy, yet the mechanisms
responsible for chronic pain in this disease are poorly understood. The up-regulation of the …
responsible for chronic pain in this disease are poorly understood. The up-regulation of the …
Long-lasting anti-inflammatory and antinociceptive effects of acute ammonium glycyrrhizinate administration: pharmacological, biochemical, and docking studies
The object of the study was to estimate the long-lasting effects induced by ammonium
glycyrrhizinate (AG) after a single administration in mice using animal models of pain and …
glycyrrhizinate (AG) after a single administration in mice using animal models of pain and …
Retracted: aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal …
VL Keleshian, HR Modi, SI Rapoport… - Journal of …, 2013 - Wiley Online Library
Aging is a risk factor for Alzheimer's disease (AD) and is associated with cognitive decline.
However, underlying molecular mechanisms of brain aging are not clear. Recent studies …
However, underlying molecular mechanisms of brain aging are not clear. Recent studies …