Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …

Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Currently, the clinic's treatment of acute/chronic wounds is still unsatisfactory due to the lack
of functional and appropriate wound dressings. Intelligent and multifunctional dressings are …

In modern medicine, bone and dental loss and defects are common and widespread
morbidities, for which regenerative therapy has shown great promise. Mesenchymal stem …

Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Stem cell senescence increases alongside the progressive functional declines that
characterize aging. The effects of extracellular vesicles (EVs) are now attracting intense …

A grade 3 burn is a nonstatic fatal injury, which can lead to complete damage to the skin
structure, accompanied by a series of symptoms such as persistent inflammation, pain …

Melatonin is a signal molecule that modulates the biological circadian rhythms of
vertebrates. Melatonin deficiency is thought to be associated with several disorders …