Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …

Ultrasound (US)-triggered sonodynamic therapy (SDT) can solve the critical issue of low
tissue-penetrating depth of traditional phototriggered therapies, but the SDT efficacy is still …

Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Antisense oligonucleotides (ASOs) are promising tools for gene silencing and have been
exploited as therapeutics for human disease. However, delivery of therapeutic ASOs to …

Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also
known across the globe for its therapeutic and medicinal benefits. The active moiety of …

As traditional anticancer treatments fail to significantly improve the prognoses, exploration of
therapeutic modalities is urgently needed. Herein, a biomimetic magnetosome is …