Pyroptosis is mainly considered as a new pro-inflammatory mediated-programmed cell
death. In addition, pyroptosis is described by gasdermin-induced pore formation on the …

Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality
worldwide. Despite broad literature including basic and translational scientific studies, many …

The Golgi apparatus serves as a receiving station where proteins from the endoplasmic
reticulum (ER) are further processed before being sent to other cellular compartments. In …

The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3,
connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome …

The NLRP3 inflammasome is a crucial constituent of the body's innate immune system, and
a multiprotein platform which is initiated by pattern recognition receptors (PRRs). Its …

The activation of NLR family pyrin domain containing 3 (NLRP3) inflammasome can be
induced by a wide spectrum of activators. This is unlikely achieved by the binding of different …

Amorphous silica nanoparticles (SNPs) are widely used in biomedical applications and
consumer products. Little is known, however, about their genotoxicity and potential to induce …

The field of cell death has witnessed significant advancements since the initial discovery of
apoptosis in the 1970s. This review delves into the intricacies of pyroptosis, a more recently …

The complexity of the pathogenetic mechanisms of the development of chronic inflammation
in asthma determines its heterogeneity and insufficient treatment effectiveness. Nuclear …

Perinatal brain injury remains a major cause of death and life-long disability. Perinatal brain
injury is typically associated with hypoxia-ischemia and/or infection/inflammation. Both …