The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation
Atrial fibrillation (AF) is the most frequent arrhythmia in adults. The prevalence and incidence
of AF is going to increase substantially over the next few decades. Because AF increases …
of AF is going to increase substantially over the next few decades. Because AF increases …
Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation
X Hou, G Xu, Z Wang, X Zhan, H Li, R Li, W Shi… - International …, 2020 - Elsevier
Glaucocalyxin A (GLA) is a bioactive ent-kauranoid diterpenoid derived from the herbal
medicine, Rabdosia japonica var. glaucocalyx, and it has been reported to possess marked …
medicine, Rabdosia japonica var. glaucocalyx, and it has been reported to possess marked …
Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages
AM Riestra, JA Valderrama, KA Patras… - Journal of innate …, 2018 - karger.com
Trichomonas vaginalis is a sexually transmitted, eukaryotic parasite that causes
trichomoniasis, the most common nonviral, sexually transmitted disease in the USA and …
trichomoniasis, the most common nonviral, sexually transmitted disease in the USA and …
Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review
Z Zhang, Y Zhang, M Zhang, C Yu, P Yang… - Critical Reviews in …, 2023 - Taylor & Francis
Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3), a member of the
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …
[HTML][HTML] The volume regulated anion channel VRAC regulates NLRP3 inflammasome by modulating itaconate efflux and mitochondria function
X Wu, X Yi, B Zhao, Y Zhi, Z Xu, Y Cao, X Cao… - Pharmacological …, 2023 - Elsevier
The NLRP3 inflammasome is a supramolecular complex that is linked to sterile and
pathogen-dependent inflammation, and its excessive activation underlies many diseases …
pathogen-dependent inflammation, and its excessive activation underlies many diseases …
Leveraging the ATP‐P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications
Y Yin, L Wei, EA Caseley… - Medicinal Research …, 2023 - Wiley Online Library
The P2X7 receptor is an exceptional member of the P2X purinergic receptor family, with its
activation requiring high concentrations of extracellular adenosine 5ʹ‐triphosphate (ATP) …
activation requiring high concentrations of extracellular adenosine 5ʹ‐triphosphate (ATP) …
NLR family pyrin domain containing 3 (NLRP3) inflammasomes and peripheral neuropathic pain-Emphasis on microRNAs (miRNAs) as important regulators
Neuropathic pain is caused by the lesion or disease of the somatosensory system and can
be initiated and/or maintained by both central and peripheral mechanisms. Nerve injury …
be initiated and/or maintained by both central and peripheral mechanisms. Nerve injury …
[HTML][HTML] Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome
ZZ Qian, QY Wang, ZS Qiu, DY Li, CC Zhang… - Journal of …, 2022 - Springer
Acute respiratory distress syndrome (ARDS), caused by noncardiogenic pulmonary edema
(PE), contributes significantly to Coronavirus 2019 (COVID-19)-associated morbidity and …
(PE), contributes significantly to Coronavirus 2019 (COVID-19)-associated morbidity and …
Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization
Q Qin, G Xu, X Zhan, Z Wang, Y Wang, H Liu… - Molecular …, 2021 - Elsevier
Brevilin A (BA), is a natural biologically active ingredient derived from Centipeda minima
with several reports of anti-cancer, while its anti-inflammatory activity is rarely reported …
with several reports of anti-cancer, while its anti-inflammatory activity is rarely reported …
ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome
X Wu, J Lv, S Zhang, X Yi, Z Xu, Y Zhi, B Zhao… - Acta Pharmacologica …, 2022 - nature.com
Dysregulation of NLRP3 inflammasome results in uncontrolled inflammation, which
participates in various chronic diseases. TWIK2 potassium channel mediates potassium …
participates in various chronic diseases. TWIK2 potassium channel mediates potassium …