The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation

X Wang, X Chen, D Dobrev, N Li - Pflügers Archiv-European Journal of …, 2021 - Springer
Atrial fibrillation (AF) is the most frequent arrhythmia in adults. The prevalence and incidence
of AF is going to increase substantially over the next few decades. Because AF increases …

Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation

X Hou, G Xu, Z Wang, X Zhan, H Li, R Li, W Shi… - International …, 2020 - Elsevier
Glaucocalyxin A (GLA) is a bioactive ent-kauranoid diterpenoid derived from the herbal
medicine, Rabdosia japonica var. glaucocalyx, and it has been reported to possess marked …

Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages

AM Riestra, JA Valderrama, KA Patras… - Journal of innate …, 2018 - karger.com
Trichomonas vaginalis is a sexually transmitted, eukaryotic parasite that causes
trichomoniasis, the most common nonviral, sexually transmitted disease in the USA and …

Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review

Z Zhang, Y Zhang, M Zhang, C Yu, P Yang… - Critical Reviews in …, 2023 - Taylor & Francis
Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3), a member of the
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …

[HTML][HTML] The volume regulated anion channel VRAC regulates NLRP3 inflammasome by modulating itaconate efflux and mitochondria function

X Wu, X Yi, B Zhao, Y Zhi, Z Xu, Y Cao, X Cao… - Pharmacological …, 2023 - Elsevier
The NLRP3 inflammasome is a supramolecular complex that is linked to sterile and
pathogen-dependent inflammation, and its excessive activation underlies many diseases …

Leveraging the ATP‐P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications

Y Yin, L Wei, EA Caseley… - Medicinal Research …, 2023 - Wiley Online Library
The P2X7 receptor is an exceptional member of the P2X purinergic receptor family, with its
activation requiring high concentrations of extracellular adenosine 5ʹ‐triphosphate (ATP) …

NLR family pyrin domain containing 3 (NLRP3) inflammasomes and peripheral neuropathic pain-Emphasis on microRNAs (miRNAs) as important regulators

P Basu, C Maier, DL Averitt, A Basu - European Journal of Pharmacology, 2023 - Elsevier
Neuropathic pain is caused by the lesion or disease of the somatosensory system and can
be initiated and/or maintained by both central and peripheral mechanisms. Nerve injury …

[HTML][HTML] Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome

ZZ Qian, QY Wang, ZS Qiu, DY Li, CC Zhang… - Journal of …, 2022 - Springer
Acute respiratory distress syndrome (ARDS), caused by noncardiogenic pulmonary edema
(PE), contributes significantly to Coronavirus 2019 (COVID-19)-associated morbidity and …

Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization

Q Qin, G Xu, X Zhan, Z Wang, Y Wang, H Liu… - Molecular …, 2021 - Elsevier
Brevilin A (BA), is a natural biologically active ingredient derived from Centipeda minima
with several reports of anti-cancer, while its anti-inflammatory activity is rarely reported …

ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome

X Wu, J Lv, S Zhang, X Yi, Z Xu, Y Zhi, B Zhao… - Acta Pharmacologica …, 2022 - nature.com
Dysregulation of NLRP3 inflammasome results in uncontrolled inflammation, which
participates in various chronic diseases. TWIK2 potassium channel mediates potassium …