Dehydration of a crystal hydrate at subglacial temperatures

AC Eaby, DC Myburgh, A Kosimov, M Kwit… - Nature, 2023 - nature.com
Water is one of the most important substances on our planet. It is ubiquitous in its solid,
liquid and vaporous states and all known biological systems depend on its unique chemical …

Physico-geometrical kinetic aspects of the thermal dehydration of trehalose dihydrate

M Hara, T Okazaki, NV Muravyev… - The Journal of Physical …, 2022 - ACS Publications
When linearly heating trehalose dihydrate (TH-DH) at a relatively high heating rate (β≥ 1.5
K min–1), the thermal dehydration begins in the solid state and transitions to the liquid state …

Physico-geometrical kinetic insight into multistep thermal dehydration of calcium hydrogen phosphate dihydrate

M Hara, N Koga - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
The origin of the multistep thermal dehydration of calcium hydrogen phosphate dihydrate
(dibasic calcium phosphate dihydrate (DCPD)) to form γ-calcium diphosphate (γ-calcium …

Polymorphic Structure Determination of the Macrocyclic Drug Paritaprevir by MicroED

G Bu, E Danelius, LHE Wieske, T Gonen - Advanced biology, 2024 - Wiley Online Library
Paritaprevir is an orally bioavailable, macrocyclic drug used for treating chronic Hepatitis C
virus (HCV) infection. Its structures have been elusive to the public until recently when one of …

[PDF][PDF] Unusual shape-preserved pathway of a core-shell phase transition triggered by orientational disorder

M Li, W Tang, J Gong - IUCrJ, 2023 - journals.iucr.org
The ubiquitous presence of crystal defects provides great potential and opportunities to
construct the desired structure (hence with the desired properties) and tailor the synthetic …

Dehydration as a Preparative Tool in the Crystal Structure Landscape Investigations of Tenofovir

O Kaszubowski, K Ślepokura, KN Truong… - Crystal Growth & …, 2024 - ACS Publications
In this work, we present the use of diffraction-guided dehydration and the complementary
use of various diffraction techniques (including X-ray and electron diffraction) to fully explore …

Elucidating the Dehydration Pathways of K2CO3·1.5H2O

J Aarts, N Mazur, HR Fischer, OCG Adan… - Crystal Growth & …, 2024 - ACS Publications
Potassium carbonate sesquihydrate has previously been identified as a promising material
for thermochemical energy storage. The hydration and cyclic behavior have been …

Evidence of a New Crystalline Phase of Prednisolone Obtained from the Study of the Hydration–Dehydration Mechanisms of the Sesquihydrate

A Lemercier, N Couvrat, Y Cartigny, M Sanselme… - Pharmaceutics, 2023 - mdpi.com
The dehydration of prednisolone sesquihydrate is studied and characterized by different
physico-chemical analysis methods. The meticulous study of this dehydration led to the …

Density Functional Theory and Density Functional Tight Binding Studies of Thiamine Hydrochloride Hydrates

E Napiórkowska, Ł Szeleszczuk, K Milcarz, DM Pisklak - Molecules, 2023 - mdpi.com
Thiamine hydrochloride (THCL), also known as vitamin B1, is an active pharmaceutical
ingredient (API), present on the list of essential medicines developed by the WHO, which …

[HTML][HTML] The Continuous and Reversible Transformation of the Polymorphs of an MGAT2 Inhibitor (S-309309) from the Anhydrate to the Hydrate in Response to …

T Miyano, K Sugita, H Ueda - Pharmaceutics, 2024 - mdpi.com
Polymorphic control is vital for the quality control of pharmaceutical crystals. Here, we
investigated the relationship between the hydrate and anhydrate polymorphs of a …