[HTML][HTML] Chronic pain in musculoskeletal diseases: Do you know your enemy?

R Bonanni, I Cariati, V Tancredi, R Iundusi… - Journal of Clinical …, 2022 - mdpi.com
Musculoskeletal pain is a condition that characterises several diseases and represents a
constantly growing issue with enormous socio-economic burdens, highlighting the …

[HTML][HTML] Autophagy and polyphenols in osteoarthritis: a focus on epigenetic regulation

C Arias, LA Salazar - International journal of molecular sciences, 2021 - mdpi.com
Autophagy is an intracellular mechanism that maintains cellular homeostasis in different
tissues. This process declines in cartilage due to aging, which is correlated with …

[HTML][HTML] Molecular and cellular mechanisms of osteoporosis

IV Zhivodernikov, TV Kirichenko, YV Markina… - International Journal of …, 2023 - mdpi.com
Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

[HTML][HTML] Role of the Vitamin D Receptor (VDR) in the pathogenesis of osteoporosis: a genetic, epigenetic and molecular pilot study

B Gasperini, VV Visconti, C Ciccacci, A Falvino… - Genes, 2023 - mdpi.com
The vitamin D receptor (VDR) regulates bone development and calcium homeostasis,
suggesting a central role in musculoskeletal diseases such as osteoporosis (OP). Several …

[HTML][HTML] Epigenetic modifications in spinal ligament aging

Q Xiang, Y Zhao, J Lin, S Jiang, W Li - Ageing Research Reviews, 2022 - Elsevier
Spinal stenosis is a common degenerative spine disorder in the aged population and the
spinal ligament aging is a main contributor to this chronic disease. However, the underlying …

[HTML][HTML] DNA methylation–mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation

D Xiao, L Fang, Z Liu, Y He, J Ying… - The Journal of …, 2024 - Am Soc Clin Investig
Challenging skeletal repairs are frequently seen in patients experiencing systemic
inflammation. To tackle the complexity and heterogeneity of the skeletal repair process, we …

[HTML][HTML] Therapeutic approach of natural products that treat osteoporosis by targeting epigenetic modulation

G Zhang, Z Liu, Z Li, B Zhang, P Yao, Y Qiao - Frontiers in Genetics, 2023 - frontiersin.org
Osteoporosis (OP) is a metabolic disease that affects bone, resulting in a progressive
decrease in bone mass, quality, and micro-architectural degeneration. Natural products …

[HTML][HTML] Methylation of the Vitamin D Receptor Gene in Human Disorders

B Gasperini, A Falvino, E Piccirilli, U Tarantino… - International Journal of …, 2023 - mdpi.com
The Vitamin D Receptor (VDR) mediates the actions of 1, 25-Dihydroxvitamin D3 (1, 25 (OH)
2D3), which has important roles in bone homeostasis, growth/differentiation of cells, immune …

RETRACTED ARTICLE: Methyl-CpG-binding protein 2 promotes osteogenic differentiation of bone marrow mesenchymal stem cells through regulating forkhead box …

W Ji, X Sun - Bioengineered, 2022 - Taylor & Francis
Statement of Retraction We, the Editors and Publisher of the journal Bioengineered, have
retracted the following article: Weiqin Ji & Xiaotong Sun (2022) Methyl-CpG-binding protein …

DNA methyltransferase 3 beta mediates the methylation of the microRNA-34a promoter and enhances chondrocyte viability in osteoarthritis

S Xiong, Y Zhao, T Xu - Bioengineered, 2021 - Taylor & Francis
Osteoarthritis (OA) is characterized by destruction of articular cartilage with an imbalance
between synthesis and degradation of extracellular matrix (ECM). In the current study, we …