Abdominal aortic aneurysms (AAA) are prevalent among older adults and can cause
significant morbidity and mortality if not addressed in a timely fashion. Their etiology remains …

Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs
that inhibit platelet aggregation have been shown to be effective in CVD treatment. However …

Abdominal aortic aneurysm (AAA) is a lethal cardiovascular disease, and there is no proven
drug treatment for this condition. In this study, by using the Connectivity Map (CMap) …

The triggering receptor expressed on myeloid cells 1 (TREM-1) drives inflammatory
responses in several cardiovascular diseases but its role in abdominal aortic aneurysm …

Background The protective effect of metformin (MET) on abdominal aortic aneurysm (AAA)
has been reported. However, the related mechanism is still poor understood. In this study …

Background and aims Abdominal aortic aneurysm (AAA) is characterized by infiltration of
inflammatory cells, extracellular matrix (ECM) degradation, and dysfunction of vascular …

The gut microbiota plays an important role in a variety of cardiovascular diseases. The
probiotics screened based on microbiota can effectively improve metabolism and immune …

Abdominal Aortic aneurysm (AAA) is associated with chronic inflammation, cells apoptosis,
and impairment of autophagy. BP-1-102, a novel potent STAT3 inhibitor, has been recently …

Objective: Abdominal aortic aneurysm is characterized by the progressive loss of aortic
integrity and accumulation of inflammatory cells primarily macrophages. We previously …

The long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) has been
implicated in the progression of abdominal aortic aneurysms (AAA). However, the detailed …