Introduction: Pneumocystis jirovecii (PJ) is an opportunistic fungal pathogen that can cause
severe pneumonia in immunocompromised hosts. Risk factors for Pneumocystis jirovecii …

During the past 3 decades, the combination of trimethoprim and sulfamethoxazole has
occupied a central role in the treatment of various commonly encountered infections and has …

We performed a search using MEDLINE (1950 to August 2011) and Embase (1980 to 2011),
along with a manual review of relevant bibliographies. We used the permuted index search …

The distal tubule of the mammalian kidney, defined as the region between the macula densa
and the collecting duct, is morphologically and functionally heterogeneous. This …

After 25 years of use in the United States, trimethoprimsulfamethoxazole (TMP-SMX) is
widely prescribed for various indications. By virtue of sequential blockade of microbial folic …

Prescribed medications, over-the-counter drugs, and nutritional supplements are used by
many patients. Although most of these products are well tolerated, drug-induced …

Disturbances in potassium homoeostasis presenting as low or high serum potassium are
common, especially among hospitalised patients. Given the fact that untreated …

The distal tubule of the mammalian kidney can be defined as the nephron segment between
the macula densa region and the cortical collecting tubule. It comprises several …

Potassium is the principal intracellular cation, and maintenance of the distribution of
potassium between the intracellular and the extracellular compartments relies on several …

The form of renal tubular acidosis associated with hyperkalemia is usually attributable to real
or apparent hypoaldosteronism. It is therefore a common feature in diabetes and a number …