Epidemiology, pathophysiology, diagnosis, and therapy of heart failure with preserved ejection fraction in Japan
M Obokata, H Sorimachi, T Harada, K Kagami… - Journal of Cardiac …, 2023 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) is a global health care problem,
with diagnostic difficulty, limited treatment options and high morbidity and mortality rates …
with diagnostic difficulty, limited treatment options and high morbidity and mortality rates …
Obesity, preserved ejection fraction heart failure, and left ventricular remodeling
J Stencel, HR Alai, A Dhore-Patil… - Journal of Clinical …, 2023 - mdpi.com
Owing to the overwhelming obesity epidemic, preserved ejection fraction heart failure
commonly ensues in patients with severe obesity and the obese phenotype of preserved …
commonly ensues in patients with severe obesity and the obese phenotype of preserved …
Non-invasive assessment of HFpEF in mouse models: current gaps and future directions
M Villalba-Orero, P Garcia-Pavia, E Lara-Pezzi - BMC medicine, 2022 - Springer
Background Heart failure (HF) with preserved ejection fraction (HFpEF) prevalence is
increasing, and large clinical trials have failed to reduce mortality. A major reason for this …
increasing, and large clinical trials have failed to reduce mortality. A major reason for this …
Utility of E/e′ ratio during low-level exercise to diagnose heart failure with preserved ejection fraction
T Harada, M Obokata, K Kagami, H Sorimachi… - Cardiovascular …, 2023 - jacc.org
Background E/e′ ratio during exercise is the key parameter in identifying elevated
pulmonary capillary wedge pressure (PCWP), and thus heart failure with preserved ejection …
pulmonary capillary wedge pressure (PCWP), and thus heart failure with preserved ejection …
Exercise Stress Echocardiography–Based Phenotyping of Heart Failure With Preserved Ejection Fraction
Y Saito, Y Omae, T Harada, H Sorimachi… - Journal of the American …, 2024 - Elsevier
Background Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome requiring improved phenotypic classification. Previous studies have identified …
syndrome requiring improved phenotypic classification. Previous studies have identified …
Exercise stress echocardiography in the diagnostic evaluation of heart failure with preserved ejection fraction
More than half of patients with heart failure have a preserved ejection fraction (HFpEF). The
prevalence of HFpEF has been increasing worldwide and is expected to increase further …
prevalence of HFpEF has been increasing worldwide and is expected to increase further …
Impaired right atrial reserve function in heart failure with preserved ejection fraction
K Kagami, T Harada, K Yoshida, S Amanai… - Journal of the American …, 2022 - Elsevier
Background Patients with heart failure with preserved ejection fraction (HFpEF) have
multiple cardiac reserve limitations during exercise. However, no data are available …
multiple cardiac reserve limitations during exercise. However, no data are available …
Pathophysiologic and prognostic importance of cardiac power output reserve in heart failure with preserved ejection fraction
D Takizawa, T Harada, M Obokata… - European Heart …, 2024 - academic.oup.com
Aims Heart failure with preserved ejection fraction (HFpEF) is a syndrome characterized by
multiple cardiac reserve limitations during exercise. Cardiac power output (CPO) is an index …
multiple cardiac reserve limitations during exercise. Cardiac power output (CPO) is an index …
Diagnostic value of expired gas analysis in heart failure with preserved ejection fraction
Y Saito, M Obokata, T Harada, K Kagami, M Murata… - Scientific Reports, 2023 - nature.com
Cardiopulmonary exercise testing (CPET) may potentially differentiate heart failure (HF) with
preserved ejection fraction (HFpEF) from noncardiac causes of dyspnea (NCD). While …
preserved ejection fraction (HFpEF) from noncardiac causes of dyspnea (NCD). While …
Key phenotypes of heart failure with preserved ejection fraction: pathophysiologic mechanisms and potential treatment strategies
Heart failure (HF) is a growing health-care problem worldwide, with an increasing
prevalence, high mortality and hospitalization rates, and high medical costs. 1 …
prevalence, high mortality and hospitalization rates, and high medical costs. 1 …