Polycystic ovary syndrome

E Stener-Victorin, H Teede, RJ Norman… - Nature Reviews …, 2024 - nature.com
Abstract Despite affecting~ 11–13% of women globally, polycystic ovary syndrome (PCOS)
is a substantially understudied condition. PCOS, possibly extending to men's health …

The epithelial Na+ channel (ENaC) in ovarian granulosa cells modulates Ca2+ mobilization and gonadotrophin signaling for estrogen homeostasis and female …

X Ma, R Xu, J Chen, S Wang, P Hu, Y Wu… - Cell Communication and …, 2024 - Springer
Ovarian granulosa cells are essential to gonadotrophin-regulated estrogen production,
female cycle maintenance and fertility. The epithelial Na+ channel (ENaC) is associated with …

An update on the current indications for in vitro maturation

VNA Ho, TM Ho, LN Vuong… - Current Opinion in …, 2024 - journals.lww.com
Despite the possibly acknowledged limitations, the potential of in vitro maturation cannot be
denied. As this technique becomes increasingly accessible to patients and more continuous …

Assessment of active translation in cumulus-enclosed and denuded oocytes during standard in vitro maturation and early embryo development

M Dvoran, R Iyyappan, T Masek, M Pospisek… - Human …, 2024 - academic.oup.com
STUDY QUESTION Which actively translated maternal transcripts are differentially regulated
between clinically relevant in vitro and in vivo maturation (IVM) conditions in mouse oocytes …

Application of amphiregulin in IVM culture of immature human oocytes and pre-insemination culture for COCs in IVF cycles

Y Fan, J Wang, T Ye, D Yang, Q Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Amphiregulin (AR) is a growth factor that resembles the epidermal growth factor
(EGF) and serves various functions in different cells. However, no systematic studies or …

Road to in vitro maturation (IVM), from basic science to an informed clinical practice

S Makieva, JJ Fraire-Zamora, OF Ammar… - Human …, 2024 - academic.oup.com
In vitro maturation (IVM) is not a novel concept; early pioneers Miriam Menkin and John
Rock published work on IVM in the 1940s (Rock and Menkin, 1944), and initial IVF …

In Vitro Maturation, In Vitro Oogenesis, and Ovarian Longevity

SJ Silber, S Goldsmith, L Castleman, K Hayashi - Reproductive Sciences, 2024 - Springer
This paper will review a remarkable new approach to in vitro maturation “IVM” of oocytes
from ovarian tissue, based on our results with in vitro oogenesis from somatic cells. As an …

The Simulated Physiological Oocyte Maturation (SPOM) System Enhances Cytoplasmic Maturation and Oocyte Competence in Cattle

M Navarro, T Fanti, NM Ortega, M Waremkraut… - Animals, 2024 - mdpi.com
Simple Summary In vitro embryo production in cattle still needs improvement in order to
reach quality and pregnancy rates comparable to in vivo-derived embryos. One of the …

Oocyte Competence of Prepubertal Sheep and Goat Oocytes: An Assessment of Large-Scale Chromatin Configuration and Epidermal Growth Factor Receptor …

M Ferrer-Roda, D Izquierdo, A Gil, MEF Oliveira… - International journal of …, 2024 - mdpi.com
The oocyte competence of prepubertal females is lower compared to that of adults, mainly
because they originate from small follicles. In adult females, the germinal vesicle (GV) and …

In vitro maturation of oocytes in light of ovarian mitochondrial improvement: effectiveness and safety

N Petrogiannis, K Chatzovoulou, M Filippa, G Grimbizis… - Zygote, 2024 - cambridge.org
In vitro maturation of oocytes (IVM) represents an assisted reproductive technique that
involves the minimal or absence of ovarian stimulation and is beneficial to specific groups of …