[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies
Standard cancer therapies sometimes fail to deliver chemotherapeutic drugs to tumor cells
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …
Modulating tumor hypoxia by nanomedicine for effective cancer therapy
R Jahanban‐Esfahlan, M de la Guardia… - Journal of cellular …, 2018 - Wiley Online Library
Hypoxia, a characteristic feature of tumors, is indispensable to tumor angiogenesis,
metastasis, and multi drug resistance. Hypoxic avascular regions, deeply embedded inside …
metastasis, and multi drug resistance. Hypoxic avascular regions, deeply embedded inside …
Lipid nanoparticles functionalized with antibodies for anticancer drug therapy
AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …
Direct inhibition of IRF-dependent transcriptional regulatory mechanisms associated with disease
A Antonczyk, B Krist, M Sajek, A Michalska… - Frontiers in …, 2019 - frontiersin.org
Interferon regulatory factors (IRFs) are a family of homologous proteins that regulate the
transcription of interferons (IFNs) and IFN-induced gene expression. As such they are …
transcription of interferons (IFNs) and IFN-induced gene expression. As such they are …
An overview of antibody conjugated polymeric nanoparticles for breast cancer therapy
Nanoparticles (NPs) are promising drug delivery systems (DDS) for identifying and treating
cancer. Active targeting NPs can be generated by conjugation with ligands that bind …
cancer. Active targeting NPs can be generated by conjugation with ligands that bind …
Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates
TL Cuellar, D Barnes, C Nelson, J Tanguay… - Nucleic acids …, 2015 - academic.oup.com
Delivery of siRNA is a key hurdle to realizing the therapeutic promise of RNAi. By targeting
internalizing cell surface antigens, antibody–siRNA complexes provide a possible solution …
internalizing cell surface antigens, antibody–siRNA complexes provide a possible solution …
Antibody conjugation of nanoparticles as therapeutics for breast cancer treatment
Breast cancer is the most common invasive tumor in women and the second leading cause
of cancer-related death. Nanomedicine raises high expectations for millions of patients as it …
of cancer-related death. Nanomedicine raises high expectations for millions of patients as it …
Nanoparticles as a solution for eliminating the risk of mycotoxins
P Horky, S Skalickova, D Baholet, J Skladanka - Nanomaterials, 2018 - mdpi.com
Mycotoxins are toxic secondary metabolites produced by certain filamentous fungi. The
occurrence of mycotoxins in food and feed causes negative health impacts on both humans …
occurrence of mycotoxins in food and feed causes negative health impacts on both humans …