Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

After the first aminoglycoside antibiotic streptomycin being applied in clinical practice in the
mid-1940s, aminoglycoside antibiotics (AGAs) are widely used to treat clinical bacterial …

RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the
fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal …

Hfq is a ubiquitous, Sm‐like RNA binding protein found in most bacteria and some archaea.
Hfq binds small regulatory RNAs (sRNAs), facilitates base pairing between sRNAs and their …

Organisms have cellular machinery that is focused on optimum utilization of resources to
maximize growth and survival depending on various environmental and developmental …

Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

Bacteria have evolved a variety of signal transduction mechanisms that generate different
outputs in response to external stimuli. Chemosensory pathways are widespread in bacteria …

The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the
base pairing between small RNAs (sRNAs) and their cognate mRNA targets. In the gram …

The major RNA-binding protein Hfq interacts with mRNAs, either alone or together with
regulatory small noncoding RNAs (sRNAs), affecting mRNA translation and degradation in …

Pseudomonas aeruginosa is a ubiquitous nosocomial opportunistic pathogen that harbors
many virulence determinants. Part of P. aeruginosa success colonizing a variety of habitats …