Many tissues and organ systems have intrinsic regeneration capabilities that are largely
driven and maintained by tissue-resident stem cell populations. In recent years, growing …

Abstract Di (2-ethylhexyl) phthalate (DEHP) and polystyrene microplastics (PS-MPs) are
new environmental pollutants that attracted increased attention. At present, the effects and …

Glucose and lipid metabolism disorders caused by insulin resistance (IR) can lead to
metabolic disorders such as diabetes, obesity, and the metabolic syndrome. Early and …

Cerebral stroke is a common neurological disease and often causes severe neurological
deficits. With high morbidity, mortality, and disability rates, stroke threatens patients' life …

6-Gingerol, one of the major pharmacologically active ingredients extracted from ginger, has
been reported experimentally to exert hepatic protection in non-alcoholic fatty liver disease …

Diabetic nephropathy (DN) is a worldwide health problem with increasing incidence.
Diosgenin (DIO) is a natural active ingredient extracted from Chinese yams (Rhizoma …

Maintenance of energy level to drive movements and material exchange with the
environment is a basic principle of life. AMP-activated protein kinase (AMPK) senses energy …

Glioblastoma WHO IV (GBM), the most common primary brain tumor in adults, is a
heterogenous malignancy that displays a reprogrammed metabolism with various fuel …

Background Accumulating evidence indicates that mitophagy is crucial for the development
of diabetic nephropathy (DN). However, little is known about the key genes involved. The …

Abstract SNF1-related protein kinase 1 (SnRK1), the plant ortholog of mammalian AMP-
activated protein kinase/fungal (yeast) Sucrose Non-Fermenting 1 (AMPK/SNF1), plays a …