[HTML][HTML] Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
J Feng, J Li, L Wu, Q Yu, J Ji, J Wu, W Dai… - Journal of Experimental & …, 2020 - Springer
Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of
cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85 …
cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85 …
The enhancement of glycolysis regulates pancreatic cancer metastasis
J Yang, B Ren, G Yang, H Wang, G Chen, L You… - Cellular and Molecular …, 2020 - Springer
Pancreatic ductal adenocarcinoma is prone to distant metastasis and is expected to become
the second leading cause of cancer-related death. In an extremely nutrient-deficient and …
the second leading cause of cancer-related death. In an extremely nutrient-deficient and …
[PDF][PDF] A comprehensive pan-cancer molecular study of gynecologic and breast cancers
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of
four gynecological types plus breast. Our aims were to identify shared and unique molecular …
four gynecological types plus breast. Our aims were to identify shared and unique molecular …
[HTML][HTML] Glucose metabolism and glucose transporters in breast cancer
E Shin, JS Koo - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Breast cancer is the most common malignancy in women worldwide and is associated with
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
[HTML][HTML] Targeting glucose metabolism to overcome resistance to anticancer chemotherapy in breast cancer
Breast cancer (BC) is the most prevalent cancer in women. BC is heterogeneous, with
distinct phenotypical and morphological characteristics. These are based on their gene …
distinct phenotypical and morphological characteristics. These are based on their gene …
Emerging roles of aerobic glycolysis in breast cancer
Z Wu, J Wu, Q Zhao, S Fu, J Jin - Clinical and Translational Oncology, 2020 - Springer
Altered aerobic glycolysis is a well-recognized characteristic of cancer cell energy
metabolism, known as the Warburg effect. Even in the presence of abundant oxygen, a …
metabolism, known as the Warburg effect. Even in the presence of abundant oxygen, a …
[HTML][HTML] Role of PFKFB3 and PFKFB4 in cancer: genetic basis, impact on disease development/progression, and potential as therapeutic targets
Simple Summary Recently, our understanding of PFK-2 isozymes, particularly with regards
to their roles in cancer, has developed significantly. This review aims to compile the most …
to their roles in cancer, has developed significantly. This review aims to compile the most …
The emerging role of targeting cancer metabolism for cancer therapy
Glucose, as the main consuming nutrient of the body, faces different destinies in cancer
cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce …
cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce …
Treatment against glucose-dependent cancers through metabolic PFKFB3 targeting of glycolytic flux
Reprogrammed metabolism and high energy demand are well-established properties of
cancer cells that enable tumor growth. Glycolysis is a primary metabolic pathway that …
cancer cells that enable tumor growth. Glycolysis is a primary metabolic pathway that …
[HTML][HTML] The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma
F Xu, Y Guan, L Xue, S Huang, K Gao, Z Yang… - BMC cancer, 2020 - Springer
Background Glycolysis is a central metabolic pathway for tumor cells. However, the potential
roles of glycolysis-related genes in renal cell carcinoma (RCC) have not been investigated …
roles of glycolysis-related genes in renal cell carcinoma (RCC) have not been investigated …