Mitochondria in innate immunity
D Arnoult, F Soares, I Tattoli, SE Girardin - EMBO reports, 2011 - embopress.org
Mitochondria are cellular organelles involved in host‐cell metabolic processes and the
control of programmed cell death. A direct link between mitochondria and innate immune …
control of programmed cell death. A direct link between mitochondria and innate immune …
Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review
The inflammation process in the human body plays a central role in the pathogenesis of
many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a …
many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a …
When it comes to an end: oxidative stress crosstalk with protein aggregation and neuroinflammation induce neurodegeneration
P Michalska, R León - Antioxidants, 2020 - mdpi.com
Neurodegenerative diseases are characterized by a progressive loss of neurons in the brain
or spinal cord that leads to a loss of function of the affected areas. The lack of effective …
or spinal cord that leads to a loss of function of the affected areas. The lack of effective …
Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs" fertilizer"
MP Lisanti, UE Martinez-Outschoorn, Z Lin, S Pavlides… - Cell cycle, 2011 - Taylor & Francis
In 1889, Dr. Stephen Paget proposed the “seed and soil” hypothesis, which states that
cancer cells (the seeds) need the proper microenvironment (the soil) for them to grow …
cancer cells (the seeds) need the proper microenvironment (the soil) for them to grow …
Molecular basis of asbestos-induced lung disease
G Liu, P Cheresh, DW Kamp - Annual Review of Pathology …, 2013 - annualreviews.org
Asbestos causes asbestosis and malignancies by molecular mechanisms that are not fully
understood. The modes of action underlying asbestosis, lung cancer, and mesothelioma …
understood. The modes of action underlying asbestosis, lung cancer, and mesothelioma …
Biochemical and molecular impacts of glyphosate-based herbicide on the gills of common carp
J Ma, J Zhu, W Wang, P Ruan, S Rajeshkumar… - Environmental pollution, 2019 - Elsevier
Abstract Glyphosate (GLY)-based herbicide, one of the most widely used herbicides, might
cause a series of environmental problems and pose a toxicological risk to aquatic …
cause a series of environmental problems and pose a toxicological risk to aquatic …
Comparison of anti-oxidant and anti-inflammatory effects between fresh and aged black garlic extracts
YY Jeong, JH Ryu, JH Shin, MJ Kang, JR Kang, J Han… - Molecules, 2016 - mdpi.com
Numerous studies have demonstrated that aged black garlic (ABG) has strong anti-oxidant
activity. Little is known however regarding the anti-inflammatory activity of ABG. This study …
activity. Little is known however regarding the anti-inflammatory activity of ABG. This study …
Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics
M Guha, NG Avadhani - Mitochondrion, 2013 - Elsevier
Mitochondria play a central role not only in energy production but also in the integration of
metabolic pathways as well as signals for apoptosis and autophagy. It is becoming …
metabolic pathways as well as signals for apoptosis and autophagy. It is becoming …
TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection
Human respiratory syncytial virus (RSV) constitute highly pathogenic virus that cause severe
respiratory diseases in newborn, children, elderly and immuno-compromised individuals …
respiratory diseases in newborn, children, elderly and immuno-compromised individuals …
COVID‐19: Proposing a Ketone‐Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
PC Bradshaw, WA Seeds, AC Miller… - Oxidative Medicine …, 2020 - Wiley Online Library
Human SARS‐CoV‐2 infection is characterized by a high mortality rate due to some patients
developing a large innate immune response associated with a cytokine storm and acute …
developing a large innate immune response associated with a cytokine storm and acute …