Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …

Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …

Metabolic plasticity, which determines tumour growth and metastasis, is now understood to
be a flexible and context-specific process in cancer metabolism. One of the major pathways …

A new series of acrylic acid and acrylate ester derivatives as modified analogs of tubulin
polymerization inhibitors were designed and synthesized. The antiproliferative activity of the …

Lung adenocarcinoma (LUAD) is one of the leading causes of cancer-related death
worldwide. Epithelial-mesenchymal transition (EMT) plays an important role in malignant …

Chloroquine (CQ) and its derivate hydroxychloroquine (HCQ), the compounds with
recognized ability to suppress autophagy, have been tested in experimental works and in …

The immune system and autophagy share a functional relationship. Both innate and
adaptive immune responses involve autophagy and, depending on the disease's origin and …

Novel N, N‐disubstituted benzimidazolium salts were efficaciously synthesized in moderate
to high yields and identified via 1H NMR and 13C NMR analyses. These compounds were …

Objective: Breast cancer is the main reason for cancer-related death in women. Britannin is
a sesquiterpene lactone compound derived from Inula aucheriana with anti-tumor …

Background The cancer risk in rheumatoid arthritis (RA) patients has been discussed.
Hydroxychloroquine (HCQ) may exert protective effects against malignancy. The study …