TMIGD1: Emerging functions of a tumor supressor and adhesion receptor

EM Thüring, C Hartmann, YA Schwietzer, K Ebnet - Oncogene, 2023 - nature.com
The development of multicellular organisms depends on cell adhesion molecules (CAMs)
that connect cells to build tissues. The immunoglobulin superfamily (IgSF) constitutes one of …

Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …

The role of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer

L Götz, U Rueckschloss, G Balk, V Pfeiffer… - Frontiers in …, 2023 - frontiersin.org
The Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), also known
as CD66a, is a member of the immunoglobulin superfamily. CEACAM1 was shown to be a …

Tumor microenvironment-induced tumor cell plasticity: relationship with hypoxic stress and impact on tumor resistance

RF Zaarour, M Ribeiro, B Azzarone, S Kapoor… - Frontiers in …, 2023 - frontiersin.org
The role of tumor interaction with stromal components during carcinogenesis is crucial for
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …

Precise Capture and Dynamic Release of Circulating Liver Cancer Cells with Dual‐Histidine‐Based Cell Imprinted Hydrogels

W Sun, X You, X Zhao, X Zhang, C Yang… - Advanced …, 2024 - Wiley Online Library
Circulating tumor cells (CTCs) detection presents significant advantages in diagnosing liver
cancer due to its noninvasiveness, real‐time monitoring, and dynamic tracking. However …

Aptamers as potential therapeutic tools for ovarian cancer: Advancements and challenges

W Szymanowski, A Szymanowska, A Bielawska… - Cancers, 2023 - mdpi.com
Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy

G Frey, APG Cugnetti, H Liu, C Xing, C Wheeler… - Mabs, 2024 - Taylor & Francis
Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein that plays
several roles in cancer biology. EpCAM is an attractive therapeutic target because of its …

Natural Compounds and Breast Cancer: Chemo-Preventive and Therapeutic Capabilities of Chlorogenic Acid and Cinnamaldehyde

Y Olayiwola, L Gollahon - Pharmaceuticals, 2024 - mdpi.com
Globally, breast cancer is not only the most frequently diagnosed cancer but also the leading
cause of cancer death in women. Depending on breast cancer histotype, conventional …

Aptamer-functionalized quasi-ZIF-67@ methylene blue hybrid nanoprobes for the electrochemical aptasensing of epithelial cancer biomarkers

Y Ma, X Shi, Y Ding, X Zhang, J Lu, D Sun - Chemical Engineering Journal, 2024 - Elsevier
The cell surface protein epithelial cell adhesion molecule (EpCAM) has oncogenic effects,
and its overexpression is strongly correlated with tumor development. Here, an …

Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis

J Zhou, F Lan, M Liu, F Wang, X Ning… - Frontiers in …, 2024 - frontiersin.org
Osteosarcoma (OS) is a malignant tumor originating from mesenchymal tissue. Pulmonary
metastasis is usually present upon initial diagnosis, and metastasis is the primary factor …