Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system,
and have the capacity to regenerate oligodendrocytes and myelin. However, in inflammatory …

Clinical outcomes in ovarian cancer are heterogeneous, independent of common features
such as stage, response to therapy and grade. This disparity in outcomes warrants further …

The success of Mycobacterium tuberculosis as a human pathogen has been attributed to the
ability of the bacillus to proliferate inside macrophages and to induce cell death. This review …

During acute infections, a small population of effector CD8+ T cells evades terminal
differentiation and survives as long-lived memory T cells. We demonstrate that the …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Cytotoxic CD8 T cells exert their antiviral and antitumor activity primarily through the
secretion of cytotoxic granules. Degranulation activity and cytotoxic granules (perforin plus …

Mast cells are widely distributed throughout the body and express effector functions in
allergic reactions, inflammatory diseases, and host defense. Activation of mast cells results …

The modulation of host cell apoptosis by bacterial pathogens is of critical importance for the
outcome of the infection process. The capacity of Bartonella henselae and B. quintana to …

The T-cell–mediated antitumor immune response is frequently repressed in the tumor
environment by an immunologic barrier, the predominant mediators of which are thought to …

Clinical outcomes in ovarian cancer are heterogeneous even when considering common
features such as stage, response to therapy, and grade. This disparity in outcomes warrants …