Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …

Obesity represents one of the most common comorbidities in patients with heart failure and
preserved ejection fraction (HFpEF). Studies have shown that obesity is not only a …

Background Obesity is associated with physiological changes that can affect drug
pharmacokinetics. Obese individuals are underrepresented in clinical trials, leading to a lack …

Background We aimed to investigate the hazard of hospitalization for heart failure (hHF)
according to the transitions in metabolic health and obesity status. Methods The Korean …

The current classification of heart failure (HF) based on left ventricular (LV) ejection fraction
(EF) identifies a large group of patients with preserved ejection fraction (HFpEF) with …

Due to hormonal variations, heart failure with preserved ejection fraction (HFpEF) remains
prevalent in women and affects almost half of the heart failure (HF) patients. Given the yearly …

Morbid obesity remains most common cause of high output failure. The prevalence of the
obesity is growing when two-thirds of American adults already are overweight or obese …

With the rapid development of society, the incidence of metabolic syndrome (MS) is
increasing rapidly. Evidence indicated that patients diagnosed with MS usually suffered from …

Abstract Purpose of Review Heart failure with preserved ejection fraction mainly affects the
elderly. The obesity phenotype of heart failure with preserved ejection fraction reflects the …

Background The association of body mass index (BMI) with diastolic dysfunction (DD) is well
described in the literature. However, there is conflicting evidence and long-term follow-up …