Interleukin-6 (IL-6) is a pleiotrophic cytokine with a diverse range of actions including the
modulation of the peripheral and central nervous system. We have previously shown …

Intravenous immunoglobulin IVIg) is a blood product prepared from the serum of between
1000 and 15 000 donors per batch. It is the treatment of choice for patients with antibody …

Human albumin is a physiological plasmaexpander; its limited availability and high cost
make it essential to define recommendations for its appropriate use, as an alternative to …

Background: Microbial superantigens have been described to contribute to the
pathogenesis of chronic inflammatory diseases often complicated by insensitivity to …

High-dose intravenous immune globulin (IVIg) has emerged as an important therapy for
various neurologic diseases. Different interpretations of clinical trial results; the expected …

Many pathogenic microbes can induce a complex series of immunologic, endothelial-cell,
and hemorheological activation cascades and dysfunctions and can cause interactions of …

Focuses on the role of intravenous immune globulins (IVIG) in clinical practice. Earliest use
of human immunoglobulin; Uses of IVIG; Approved indications for IVIG; Off-label uses for …

Panton Valentine leukocidin (PVL) may be responsible for pulmonary necrosis in necrotizing
Staphylococcus aureus pneumonia, a highly lethal infection. Commercial intravenous …

BACKGROUND: Intravenous immune globulin (IVIG) has been approved by the Food and
Drug Administration (FDA) for use in 6 conditions: immune thrombocytopenic purpura (ITP) …

Sepsis represents a dysregulated host response to infection, the extent of which determines
the severity of organ dysfunction and subsequent outcome. All trialled immunomodulatory …