Small cell lung cancer (SCLC) is a lethal form of lung cancer. Here, we develop a
quantitative multiplexed approach on the basis of lentiviral barcoding with somatic CRISPR …

Vasculogenic mimicry (VM) formation by cancer cells is known to play a crucial role in tumor
progression, but its detailed mechanism is unclear. In the present study, we focused on …

Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the
tumour of origin. They bear specific intra-and extra-cellular protein markers aiding in their …

Various aggressive cancers, including pancreatic cancer, produce functional blood vessels
by neovascularization. Tumor vasculogenic mimicry (VM) promotes cancer progression and …

Background Optoacoustic tomography (OT) of breast tumour oxygenation is a promising
new technique, currently in clinical trials, which may help to determine disease stage and …

Noncoding ribonucleic acids (ncRNAs) are closely associated with tumor initiation, growth,
and progress in lung cancer. Long ncRNAs (lncRNAs), as one of the three subclasses of …

Small-cell lung cancer (SCLC) represents 15% of all lung cancers and it is clinically the most
aggressive type, being characterized by a tendency for early metastasis, with two-thirds of …

Background Radioresistance inducing by hypoxic microenvironment of hepatocellular
carcinoma is a major obstacle to clinical radiotherapy. Advanced nanomedicine provides an …

The single cell is considered the basic unit of biology, and the pursuit of understanding how
heterogeneous populations of cells can functionally coexist in tissues, organisms, microbial …

Tumor progression depends primarily on vascular supply, which is facilitated by angiogenic
activity within the malignant tissue. Non-small cell lung cancer (NSCLC) is a highly …