Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess
thousands of individual processes, which extend out into the neuropil, interacting with …

The promise of engineering specific cell types from stem cells and rebuilding damaged or
diseased tissues has fascinated stem cell researchers and clinicians over last few decades …

Background Sex differences in incidence and/or presentation of schizophrenia (SCZ), major
depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for …

Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …

Nerve fibers and vessels play important roles in bone formation, and inadequate innervation
in the bone defect area can delay the regeneration process. However, there are few studies …

Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Canonical Wnt signaling, which is transduced by β‐catenin and lymphoid enhancer factor
1/T cell‐specific transcription factors (LEF1/TCFs), regulates many aspects of metazoan …

The development of a functional nervous system entails establishing connectivity between
appropriate synaptic partners. During axonal pathfinding, the developing axon navigates …

Increased fructose intake is a global issue, especially in mothers. Maternal fructose
exposure during gestation and lactation can affect learning and memory in offspring; …

A major challenge in regulatory developmental neurotoxicity (DNT) assessment is lack of
toxicological information for many compounds. Therefore, the Test Guidelines programme of …