Valproic acid (VPA) is considered to be a drug of first choice and one of the most frequently-
prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies …

In recent years, there has been an increasing interest in the potential involvement of
neuroinflammation in the pathogenesis of epilepsy. Specifically, the role of innate immunity …

Objective A single-center, single-blind, parallel-group, randomized clinical trial was
performed to test the null hypothesis that adrenocorticotropic hormone is not superior to high …

We systematically reviewed the files of 51 infants presenting with infantile spasms and
hypsarrhythmia in order to study the initial treatment strategies and the long term outcome …

Purpose This study was intended to document the clinical profile and treatment outcome of
West syndrome in children attending a tertiary care center in Northern India. Method Data …

West syndrome (WS) is an early life epileptic encephalopathy associated with infantile
spasms, interictal electroencephalography (EEG) abnormalities including high amplitude …

Infantile spasms is an epileptic encephalopathy of early infancy with specific clinical and
electroencephalographic (EEG) features, limited treatment options, and a poor prognosis …

Purpose: Pyridoxine‐dependent epilepsy (PDE) is characterized by therapy‐resistant
seizures (TRS) responding to intravenous (IV) pyridoxine. PDE can be identified by …

The authors report their experience with intravenous methylprednisolone for the treatment of
infantile spasms. A pulse dose of 20 mg/kg intravenous methylprednisolone on each of 3 …

Purpose: Ketogenic diet therapy (KD) has been used to treat children with refractory
generalized epilepsy. We herein reported the efficacy of KD for West syndrome (WS) …