The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

An increasing amount of research effort is being directed toward investigating the neural
bases of social cognition from a systems neuroscience perspective. Evidence from multiple …

The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

Prefrontal cortex (PFC) means different things to different people. In recent years, there has
been a major increase in publications on the PFC, especially using mice. However …

The ability to adaptively regulate emotion is essential for mental and physical well-being.
How should we organize the myriad ways people attempt to regulate their emotions? We …

Recent breakthroughs in artificial intelligence (AI) have enabled machines to plan in tasks
previously thought to be uniquely human. Meanwhile, the planning algorithms implemented …

Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

Meditation training can improve mood and emotion regulation, yet the neural mechanisms of
these affective changes have yet to be fully elucidated. We evaluated the impact of long-and …

In our TICS Review in 2004, we proposed that a sector of the right inferior frontal cortex
(rIFC) in humans is critical for inhibiting response tendencies. Here we survey new …