Background Every day the skin is constantly exposed to several harmful factors that induce
oxidative stress. When the cells are incapable to maintain the balance between antioxidant …

Background Sustained liver fibrosis may lead to cirrhosis. Activated hepatic stellate cells
(HSCs) are crucial for liver fibrosis development. Ferroptosis, a newly iron-dependent …

Chitooligosaccharide (COS), found in both insects and marine sources, has several
bioactivities, such as anti-inflammation and antioxidant activities. However, the mechanism …

Background The annual incidence of diabetic foot ulcers (DFUs) has been reported to vary
from 0.2% to 11% in diabetes-specific clinical settings and less than 0.1% to 8% in …

Background Naegleria fowleri is a brain-eating amoeba causing a fatal brain infection called
primary amoebic meningoencephalitis (PAM). Despite its high mortality over 95%, effective …

Acetate is associated with adipocyte differentiation and lipid deposition. To further develop
this scientific point, obese mice on a high-fat diet were given an intragastric administration of …

Background Addressing brain metastases in cancer presents substantial challenges due to
limited therapeutic options and high mortality rates. In clinical practice, the amalgamation of …

Introduction Fungus-derived secondary metabolites are fascinating with biomedical potential
and chemical diversity. Mining endophytic fungi for drug candidates is an ongoing process …

The roots of Astilbe grandis, known as “Ma sang gou bang”, are used as a Miao traditional
medicine with anti-inflammatory and analgesic properties. However, the active components …

Cirsium japonicum is a medicinal plant that has been used due to its beneficial properties.
However, extensive information regarding its therapeutic potential is scarce in the scientific …