Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook

H Li, H Kim, F Xu, J Han, Q Yao, J Wang, K Pu… - Chemical Society …, 2022 - pubs.rsc.org
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms

C Caglayan, FM Kandemir, E Darendelioğlu… - Life Sciences, 2021 - Elsevier
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …

Biphasic functions of sodium fluoride (NAF) in soft and in hard periodontal tissues

X Wang, N Tewari, F Sato, K Tanimoto… - International Journal of …, 2022 - mdpi.com
Sodium fluoride (NaF) is widely used in clinical dentistry. However, the administration of
high or low concentrations of NaF has various functions in different tissues. Understanding …

[HTML][HTML] Fluoride enhances generation of reactive oxygen and nitrogen species, oxidizes hemoglobin, lowers antioxidant power and inhibits transmembrane electron …

N Maheshwari, N Qasim, R Anjum… - … and Environmental Safety, 2021 - Elsevier
Fluoride is a widespread environmental pollutant that at high levels exerts numerous
deleterious effects on human health. The toxic effects of fluoride are a matter of serious …

Moringa Oleifera Leaf Extract Repairs the Oxidative Misbalance following Sub-Chronic Exposure to Sodium Fluoride in Nile Tilapia Oreochromis niloticus

NF Ahmed, KM Sadek, MK Soliman, RH Khalil… - Animals, 2020 - mdpi.com
Simple Summary The present study investigated the antioxidant effect of ethanolic extract of
Moringa Oleifera (MO) leaves against sodium fluoride-induced toxicity in Nile tilapia. It is …

Chronic exposure to sodium fluoride triggers oxidative biochemistry misbalance in mice: effects on peripheral blood circulation

GHN Miranda, BAQ Gomes… - Oxidative medicine …, 2018 - Wiley Online Library
The excessive fluoride (F) exposure is associated with damage to cellular processes of
different tissue types, due to changes in enzymatic metabolism and breakdown of redox …

Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells

X Li, L Meng, F Wang, X Hu, Y Yu - Molecular and cellular biochemistry, 2019 - Springer
Fluorosis and bone pathologies can be caused by chronic and/or excessive fluoride intake.
Despite this, few studies have been conducted on the cellular mechanisms underlying …

SIRT1 suppresses p53-dependent apoptosis by modulation of p21 in osteoblast-like MC3T3-E1 cells exposed to fluoride

X Gu, Z Wang, J Gao, D Han, L Zhang, P Chen, G Luo… - Toxicology in Vitro, 2019 - Elsevier
Fluoride is very crucial for development of teeth and bones. Excessive fluoride, however,
causes damage to teeth and bones resulting in serious public health problem. SIRT1 …

Mitochondrial-targeted near-infrared fluorescence probe for selective detection of fluoride ions in living cells

X Xu, W Chen, M Yang, XJ Liu, F Wang, RQ Yu… - Talanta, 2019 - Elsevier
Abstract Fluoride ions (F−), as a strongest electron withdrawing anion of the smallest size,
have played an indispensable role in biological systems. Here a mitochondria-targeted near …

Clinical prospective assessment of genotoxic and cytotoxic effects of fluoride toothpaste and mouthwash in buccal mucosal cells

E Puizina Mladinic, J Puizina, L Gavic, A Tadin - Biomedicines, 2022 - mdpi.com
Background: Fluorides are an essential component of oral hygiene products used to prevent
dental decay. Therefore, a question arises about the potential harms of joint use of …